AIR OPTIX NIGHT & DAY AQUA vs ACUVUE OASYS: What’s the Difference?


AIR OPTIX NIGHT & DAY® AQUA and ACUVUE OASYS® with HYDRACLEAR PLUS are two high-quality contact lens brands developed by leading manufacturers, Alcon and Johnson & Johnson. Both brands are great options for a contact lens wearer.

In this guide, we’ll do a comparison of AIR OPTIX NIGHT & DAY AQUA and ACUVUE OASYS with HYDRACLEAR PLUS. We’ll detail the differences between the two contact lenses, taking into consideration the wearing schedule, features, water content, and customer reviews. 

After reading this guide, you’ll have a much clearer idea about which contact lens brand is right for you. However, make sure you also follow the recommendations of your eye care professional (ECP).

Manufacturer Alcon Johnson & Johnson
Replacement schedule Monthly replacement Bi-weekly replacement
Material Lotrafilcon A (76% Polymer) Senofilcon A (62% polymer)
Water content 24% water 38% water
Vision problems corrected – Nearsightedness
– Farsightedness
– Nearsightedness
– Farsightedness
Key features – Among soft contact lenses, this brand allows the highest level of oxygen to pass through the lens
– Enables you to sleep comfortably in the contact lenses
– Provides tear film stability for maximum comfort
– Highest level of UV protection available in a contact lens
Lenses per box – 6 lenses per box (6-month supply) – 12 lenses per box (6-month supply)
– 24 lenses per box (1-year supply)


AIR OPTIX® NIGHT & DAY® AQUA and ACUVUE® OASYS with HYDRACLEAR® PLUS are two contact lens brands that are both designed to correct myopia (nearsightedness) and hyperopia (farsightedness). Both brands are also designed to provide the contact lens wearer with maximum comfort throughout the day. 

AIR OPTIX NIGHT & DAY AQUA has a 30-day replacement schedule. This brand of contact lenses is FDA-approved for extended wear of up to 30 nights. You can wear these contact lenses while awake and asleep for up to 30 nights before discarding them. However, keep in mind that you may not be able to wear these contact lenses for 30 consecutive nights. If your ECP recommends a shorter wearing schedule, then you’ll have to follow that schedule.

On the other hand, ACUVUE OASYS with HYDRACLEAR PLUS has a 14-day replacement schedule. This brand can be worn during the day and then taken out at night. It is also FDA-approved for extended wear of up to six nights and seven days.

AIR OPTIX NIGHT & DAY AQUA is one of the most comfortable contact lenses available today. These contact lenses enable high levels of oxygen to freely pass through the lens, thereby providing you with exceptional comfort whether you’re awake or asleep. 

When it comes to comfort, ACUVUE OASYS with HYDRACLEAR PLUS is also a good option. These contact lenses are specifically designed for wearers who spend time in challenging environments. If you work in a dry and dusty space like a warehouse, then you may want to consider wearing this brand of contact lenses.

Another benefit of wearing ACUVUE OASYS with HYDRACLEAR PLUS contact lenses is that they protect your eyes from UVA and UVB rays. This brand has the highest level of UV protection available in any brand of contact lenses. Unlike AIR OPTIX NIGHT & DAY AQUA, ACUVUE OASYS contact lenses have UV-blocking properties.

Here are some of our customer’s reviews for AirOptix Night and Day Aqua and Acuvue Oasys:

AIR OPTIX NIGHT & DAY AQUA contact lenses have 440 reviews with an average rating of 9.5/10 on 

“The most important thing ever, they’re comfortable hands down the most comfortable contacts I’ve had in my 20 years of wearing contacts.” -Ivan Trotter

“These are super-comfortable contacts, and they are long-lasting, so long as you clean them regularly and follow your eye doctor’s advice about how long you wear them.” -Charles Boyer

ACUVUE OASYS with HYDRACLEAR PLUS contact lenses have 747 reviews with an average rating of 9.2/10 on 

Here are some additional quotes from wearers:

“I have worn the Acuvue oasys for many years and find them the best for my needs.” -Sonia Davies

“I just switched to the Acuvue Oasys from the Acuvue 2’s, and my eyes overall just feel so much better. Way more comfortable. I advise trying them if you have not.” – Anonymous

Conclusion: which brand is right for you?

If comfort is your top priority when choosing contact lenses, then you can’t go wrong with either AIR OPTIX NIGHT & DAY AQUA or ACUVUE OASYS with HYDRACLEAR PLUS. Both brands are designed with the wearer’s comfort in mind.

First, consider your ideal wearing schedule. If you prefer not to remove your contact lenses for an extended period even when asleep, then AIR OPTIX NIGHT & DAY AQUA is a great option for you. Its 30-day replacement schedule means that you can put the contact lenses in and not worry about them for several days at a time. This brand gives maximum comfort at any time of the day, whether you’re awake or asleep. Remember to follow the guidance of your ECP in case they recommend a shorter wearing schedule. 

Are you a first-time wearer or an experienced wearer? Per the manufacturer, ACUVUE OASYS is the brand that most ECP’s prescribe for first-time contact lens wearers. If you’ve never worn contact lenses before, then you may want to consult with your ECP about prescribing this lens.