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What Is HSV Epithelial Keratitis?

HSV epithelial keratitis is a corneal infection caused by herpes simplex virus affecting the outermost corneal layer. It is the most common form of ocular herpes infection. The virus infects surface cells, leading to characteristic corneal lesions. Symptoms often develop suddenly and can affect one eye. Prompt treatment helps protect the cornea and reduce complications.

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What Is HSV Epithelial Keratitis?

HSV epithelial keratitis is a corneal infection caused by herpes simplex virus affecting the outermost corneal layer. It is the most common form of ocular herpes infection. The virus infects surface cells, leading to characteristic corneal lesions. Symptoms often develop suddenly and can affect one eye. Prompt treatment helps protect the cornea and reduce complications.

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Why Does HSV Affect the Corneal Epithelium?

The herpes simplex virus can lie dormant in nerve tissue and reactivate under certain conditions. When reactivation occurs, the virus travels along nerves to the corneal surface. The epithelial layer is vulnerable because it regenerates frequently. Viral replication damages surface cells. This leads to visible lesions during eye examination.

What Are Common Signs of HSV Epithelial Keratitis?

Symptoms often develop quickly and can worsen without treatment. Early care helps protect corneal health.

  • Eye redness and irritation
  • Pain or foreign body sensation
  • Light sensitivity
  • Blurred vision
  • Branching corneal lesions

How Is HSV Epithelial Keratitis Treated?

Treatment usually involves antiviral eye drops or oral medication. Steroid drops are avoided during active epithelial infection. Follow-up exams monitor healing and detect recurrence. Early care lowers the risk of scarring. Doctors also review triggers that may cause reactivation.

What Should You Do Right Away If You Suspect HSV Epithelial Keratitis?

Contact lenses should come out and stay out until an eye clinician clears lens wear. Prompt evaluation matters since antiviral treatment works best early and helps lower the chance of corneal scarring. Avoid using leftover steroid drops, since steroids can worsen active epithelial infection unless a clinician directs otherwise.

Frequently Asked Questions

Is HSV epithelial keratitis contagious?

The virus can spread through contact, but eye-to-eye transmission is uncommon. Good hygiene reduces risk. Doctors focus on treatment and monitoring.

Can HSV epithelial keratitis return?

Yes, recurrences are possible. The virus remains dormant in nerve tissue. Follow-up care helps manage risk.

Does HSV epithelial keratitis affect vision permanently?

Most cases heal without permanent damage. Delayed treatment can increase scarring risk. Early care supports recovery.

Should contact lenses be worn during infection?

No, contact lenses should be avoided. Wearing lenses can slow healing. Your doctor will advise when lens wear can resume.

References

1. Herpes simplex keratitis. National Eye Institute. https://www.nei.nih.gov/learn-about-eye-health/eye-conditions-and-diseases/herpes-simplex-keratitis. Accessed July 4, 2025.

2. Herpes simplex eye infections. American Academy of Ophthalmology. https://www.aao.org/eye-health/diseases/herpes-simplex-eye-infections. Accessed July 4, 2025.

3. Herpes simplex keratitis. Cleveland Clinic. https://my.clevelandclinic.org/health/diseases/24123-herpes-simplex-keratitis. Accessed July 4, 2025.

4. Eye herpes. MedlinePlus. https://medlineplus.gov/ency/article/001036.htm. Accessed July 4, 2025.

5. Herpes simplex keratitis. BMJ Best Practice. https://bestpractice.bmj.com/topics/en-us/951. Accessed July 4, 2025.