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What Is Gorlin Syndrome (Nevoid Basal Cell Carcinoma Syndrome)?

Gorlin syndrome is an inherited condition that causes frequent skin growths, jaw cysts, and bone changes. Symptoms appear during childhood or early adulthood. Patterns vary widely. Early detection helps support long-term planning.

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What Is Gorlin Syndrome (Nevoid Basal Cell Carcinoma Syndrome)?

Gorlin syndrome is an inherited condition that causes frequent skin growths, jaw cysts, and bone changes. Symptoms appear during childhood or early adulthood. Patterns vary widely. Early detection helps support long-term planning.

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What Causes Gorlin Syndrome?

Gorlin syndrome occurs due to inherited changes that affect cell growth. These changes lead to frequent skin growths and bone differences. Symptoms appear across childhood and adulthood. Monitoring helps guide long-term planning.

Common Symptoms

Skin growths, jaw cysts, sun sensitivity, and bone changes are common. Some individuals develop spine or rib differences. Symptom patterns vary.

How Is Gorlin Syndrome Diagnosed?

Diagnosis includes physical exam, imaging, and genetic testing. Doctors review skin growths and bone findings. Early identification helps plan monitoring. Screening family members may be recommended.

How Does Gorlin Syndrome Affect Daily Life?

Frequent skin growths require monitoring and occasional removal. Sun protection becomes a daily routine. Dental and bone care may be needed. Activity levels vary widely. Long-term planning supports comfort.

What Treatment Approaches Are Used?

Care involves monitoring skin growths, removing cysts when needed, and protecting the skin from sun exposure. Dental and bone care may be required. Regular screening helps detect changes early. Families receive long-term support.

When to See Your Doctor

If something feels off or your symptoms stick around longer than expected, it's a good idea to get checked. Sudden changes, discomfort that doesn't improve, or anything that affects your daily routine deserve attention. A doctor can help figure out what's going on and guide you on the right next steps.

FAQs About Gorlin Syndrome

Is it inherited?
Yes, it follows dominant patterns.

Are skin growths cancerous?
Most are noncancerous.

Can children be tested?
Yes, testing helps guide care.

References

Gorlin syndrome. MedlinePlus Genetics. https://medlineplus.gov/genetics/condition/gorlin-syndrome/. Date Accessed March 19, 2026.

Nevoid Basal Cell Carcinoma Syndrome - GeneReviews - NCBI. NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK1151/. Date Accessed March 19, 2026.

Nevoid Basal Cell Carcinoma Syndrome. National Organization for Rare Disorders. https://rarediseases.org/rare-diseases/nevoid-basal-cell-carcinoma-syndrome/. Date Accessed March 19, 2026.

Nevoid basal cell carcinoma syndrome | About the Disease. Genetic and Rare Diseases Information Center. https://rarediseases.info.nih.gov/?gard_id=0007166. Date Accessed March 19, 2026.

What Is Gorlin Syndrome?. Cleveland Clinic. https://my.clevelandclinic.org/health/diseases/22730-gorlin-syndrome. Date Accessed March 19, 2026.