R R

What Is a Uveal Angioma?

A uveal angioma is a benign overgrowth of blood vessels within the uveal tract, most often referring to a choroidal hemangioma. It can be circumscribed (a localized mass) or diffuse (a broader thickening). Some cases cause leakage and subretinal fluid that can blur vision. Many are stable, but symptomatic cases need retina specialist evaluation.

Link to This Resource Page

Provide a valuable resource to your clients or customers by linking to this resource page. Just place the following link on your website.

To display this...

What Is a Uveal Angioma?

A uveal angioma is a benign overgrowth of blood vessels within the uveal tract, most often referring to a choroidal hemangioma. It can be circumscribed (a localized mass) or diffuse (a broader thickening). Some cases cause leakage and subretinal fluid that can blur vision. Many are stable, but symptomatic cases need retina specialist evaluation.

read more about uveal angioma ...

Copy this HTML:

Copy HTML Copied!

Types and causes

Most uveal angiomas are congenital vascular hamartomas that may be discovered later in life. Circumscribed choroidal hemangioma is typically sporadic and unilateral, while diffuse choroidal hemangioma is more often associated with Sturge-Weber syndrome. The main clinical concern is whether the lesion is causing fluid under or within the retina. Classification helps guide monitoring and treatment decisions.

Symptoms

Symptoms depend on size and whether fluid reaches the macula. People may notice blurred vision, distortion, or a hyperopic shift from retinal elevation. Some cases are asymptomatic and found incidentally on a dilated exam. Sudden worsening blur, new distortion, or a new central dark spot should be evaluated promptly.

How it is diagnosed

Diagnosis starts with a dilated fundus exam to identify an orange-red choroidal lesion and any associated fluid. Optical coherence tomography (OCT) can show subretinal fluid or macular edema. B-scan ultrasonography helps assess lesion thickness and internal reflectivity, and angiography studies may be used in selected cases. Imaging is also used to distinguish hemangioma from other choroidal tumors.

Treatment and monitoring

Asymptomatic lesions without fluid may be monitored with periodic exams and imaging. Symptomatic cases with subretinal fluid are often treated with photodynamic therapy (PDT) using verteporfin to reduce leakage and stabilize vision. Other options may include laser, transpupillary thermotherapy, or radiotherapy depending on anatomy and response. Follow-up focuses on resolution of fluid and protection of macular function.

FAQs on uveal angioma

Is a uveal angioma cancer?

No. A uveal angioma, such as a choroidal hemangioma, is benign. The key goal of evaluation is to confirm the diagnosis and monitor for fluid that can affect vision.

What is the difference between circumscribed and diffuse choroidal hemangioma?

Circumscribed hemangioma is a localized vascular tumor, usually sporadic and unilateral. Diffuse hemangioma involves a broader area of the choroid and is more often linked to Sturge-Weber syndrome. Both can cause subretinal fluid and vision changes.

When is treatment recommended?

Treatment is typically recommended when the lesion causes subretinal fluid, macular edema, or documented vision decline. Photodynamic therapy with verteporfin is a common option for symptomatic cases. Your retina specialist selects treatment based on lesion location and imaging findings.

Can vision improve after treatment?

Vision may improve if fluid resolves and the macula has not developed permanent damage. Some patients mainly achieve stabilization rather than large improvement. Early treatment for macula-threatening fluid can support better outcomes.

References

Intraocular Vascular Tumors. EyeWiki (American Academy of Ophthalmology). https://eyewiki.org/Intraocular_Vascular_Tumors. Date Accessed: February 19, 2026.

New insights on circumscribed choroidal hemangioma: “bench to bedside”. Lupidi M, et al. https://pmc.ncbi.nlm.nih.gov/articles/PMC10995022/. Date Accessed: February 19, 2026.

Safety and Efficacy of Photodynamic Therapy in Treatment of Choroidal Hemangioma: A Systematic Review. Cagini C, et al. https://pmc.ncbi.nlm.nih.gov/articles/PMC10786325/. Date Accessed: February 19, 2026.

Intravitreal Bevacizumab for the Treatment of Exudative Circumscribed Choroidal Hemangiomas. PubMed Central (PMC). https://pmc.ncbi.nlm.nih.gov/articles/PMC11832178/. Date Accessed: February 19, 2026.

Diffuse choroidal hemangioma: Ophthalmic outcomes and dosimetry comparison of intensity-modulated radiation therapy and plaque brachytherapy. PubMed Central (PMC). https://pmc.ncbi.nlm.nih.gov/articles/PMC11981580/. Date Accessed: February 19, 2026.