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What is Ulcerative Colitis?

Ulcerative Colitis is a chronic inflammatory disease that causes long-lasting inflammation and sores (ulcers) in the inner lining of the large intestine (colon and rectum). It is a type of Inflammatory Bowel Disease (IBD).

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What is Ulcerative Colitis?

Ulcerative Colitis is a chronic inflammatory disease that causes long-lasting inflammation and sores (ulcers) in the inner lining of the large intestine (colon and rectum). It is a type of Inflammatory Bowel Disease (IBD).

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What is the Cause and Mechanism of Inflammation?

The cause is unknown, but it is believed to be an autoimmune disorder where the immune system attacks the lining of the colon. The inflammation is continuous and confined strictly to the lining of the large bowel, differentiating it from Crohn's disease.

What Symptoms are Associated with the Disorder?

Symptoms include bloody diarrhea, abdominal pain, rectal bleeding, and persistent urgency to have a bowel movement. Systemic symptoms like fatigue, weight loss, and fever can also occur during severe flare-ups.

How Does This Condition Impact Vision or Eye Health?

Ulcerative Colitis impacts eye health as a systemic inflammatory disorder. Patients frequently develop inflammation in the eye tissues, such as episcleritis (redness on the surface) or uveitis (inflammation inside the eye), which can cause pain and blurry vision.

Diagnosis and Treatment

Diagnosis involves an endoscopy (colonoscopy) to view the lining of the colon and take biopsies. Treatment focuses on reducing inflammation using medication (aminosalicylates, corticosteroids, or biologic drugs). Surgery may be needed to remove the colon.

What are the Long-Term Complications?

Long-term complications include severe dehydration, nutritional deficiencies, and an increased risk of developing colon cancer. Patients require frequent monitoring and screening to manage these risks.

FAQs on Ulcerative Colitis

Is this curable?

Yes, surgical removal of the colon (colectomy) is considered a definitive cure for the disease.

Is this the same as Crohn's disease?

No, Crohn's can affect the entire digestive tract in patches. Ulcerative Colitis is continuous inflammation confined to the large intestine.

Does it affect women more than men?

No, the disorder affects both men and women equally.

When to See Your Doctor

Consult a gastroenterologist if you notice blood in your stool or persistent diarrhea. Long-term UC increases the risk of colon cancer and can cause "Episcleritis", a red, painful inflammation of the eye surface that correlates with bowel flares.

References

Crohn's & Colitis Foundation. Ulcerative Colitis (crohnscolitisfoundation.org). 2024.

Mayo Clinic. Ulcerative Colitis (mayoclinic.org). 2024.

AAO. IBD and the Eye (aao.org). 2024.

StatPearls. Ulcerative Colitis (ncbi.nlm.nih.gov). 2024.