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Motrin is a trade name for medicines containing ibuprofen, a nonsteroidal anti-inflammatory drug. This page focuses on over-the-counter Motrin IB caplets containing 200 mg of ibuprofen each. They temporarily relieve minor aches and pains and reduce fever. Prescription ibuprofen tablets and children's Motrin products have different dosing instructions.
read more about motrin ...Ibuprofen inhibits cyclooxygenase enzymes involved in prostaglandin production. Prostaglandins contribute to pain, inflammation, and elevated body temperature. Reducing their production helps relieve minor pain and lower fever.
Motrin IB is used by adults and children age 12 and older for temporary relief of headache, muscle aches, minor arthritis pain, toothache, backache, menstrual cramps, common cold-related aches, and fever. Children younger than 12 require a doctor's guidance for this formulation. Patients with serious previous allergic reactions to ibuprofen or similar pain relievers must not use it.
Adults and children age 12 and older take one 200 mg caplet every four to six hours while symptoms persist. Two caplets can be taken when one does not relieve pain or fever. The maximum nonprescription dose is six caplets, equivalent to 1200 mg, in 24 hours unless a doctor directs otherwise. Food or milk can be taken with the medicine when stomach upset occurs.
Motrin IB can cause severe gastrointestinal bleeding, allergic reactions, kidney injury, and cardiovascular events, including heart attack or stroke. Risk increases with excessive doses, prolonged treatment, older age, or certain interacting medicines. Current labeling warns against use at 20 weeks or later in pregnancy unless specifically directed by a physician. Persistent pain beyond ten days or fever beyond three days requires medical evaluation.
Each Motrin IB caplet contains 200 mg of ibuprofen.
It temporarily relieves minor aches and pains, including headaches, muscle aches, toothaches, menstrual cramps, and minor arthritis pain, and reduces fever.
Adults and children age 12 and older should not exceed six 200 mg caplets, or 1200 mg, in 24 hours unless directed by a doctor.
Yes. Ibuprofen can cause serious gastrointestinal bleeding, particularly in people with certain risk factors or those taking excessive doses.
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Ibuprofen. LiverTox. https://www.ncbi.nlm.nih.gov/books/NBK547845/. Date Accessed October 16, 2026.
Ibuprofen. MedlinePlus. https://medlineplus.gov/druginfo/meds/a682159.html. Date Accessed October 16, 2026.
Ibuprofen. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Ibuprofen. Date Accessed October 16, 2026.
MOTRIN IB Ibuprofen Tablets for Fever and Pain Relief. Motrin. https://www.motrin.com/products/motrin-ib. Date Accessed October 16, 2026.