Provide a valuable resource to your clients or customers by linking to this resource page. Just place the following link on your website.
Lurasidone hydrochloride is a prescription atypical antipsychotic also marketed as Latuda. Current generic labeling includes schizophrenia in adults and adolescents age 13 through 17 and depressive episodes associated with bipolar I disorder in adults and children age 10 through 17. Adult bipolar depression treatment can be given alone or with lithium or valproate.
read more about lurasidone ...The exact therapeutic mechanism is not established. Lurasidone blocks dopamine D2 and serotonin 5-HT2A receptors and interacts with other serotonin receptor subtypes. These actions affect neurotransmitter signaling associated with psychotic and mood symptoms.
Lurasidone is used for schizophrenia in adults and adolescents age 13 through 17. It also treats bipolar I depression in adults and children age 10 through 17, with adult adjunctive use alongside lithium or valproate. It is not approved for dementia-related psychosis. Strong CYP3A4 inhibitors and strong CYP3A4 inducers are contraindicated.
Adult schizophrenia starts at 40 mg once daily with a recommended range of 40 mg to 160 mg daily. Adolescent schizophrenia uses 40 mg to 80 mg daily. Adult bipolar depression starts at 20 mg once daily with a range of 20 mg to 120 mg, while patients age 10 through 17 use 20 mg to 80 mg daily. Every dose is taken with food containing at least 350 calories.
Lurasidone carries boxed warnings for increased mortality in older adults with dementia-related psychosis and suicidal thoughts and behaviors in pediatric and young adult patients taking antidepressant therapy. Other serious concerns include neuroleptic malignant syndrome, tardive dyskinesia, metabolic changes, elevated prolactin, low white blood cell counts, orthostatic hypotension, seizures, and impaired alertness.
Lurasidone treats schizophrenia and depressive episodes associated with bipolar I disorder under age-specific criteria.
The recommended starting dose is 40 mg once daily.
The recommended starting dose is 20 mg once daily in adults and patients age 10 through 17.
Yes. Lurasidone is taken with food containing at least 350 calories.
DailyMed - LURASIDONE HYDROCHLORIDE tablet, film coated. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=6d97d871-66d3-4ed8-bbc5-0620e9f69ae5. Date Accessed October 13, 2026.
Lurasidone. LiverTox. https://www.ncbi.nlm.nih.gov/books/NBK548303/. Date Accessed October 13, 2026.
Lurasidone. MedlinePlus. https://www.medlineplus.gov/druginfo/meds/a611016.html. Date Accessed October 13, 2026.
Lurasidone. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Lurasidone. Date Accessed October 13, 2026.
Lurasidone. StatPearls. https://www.ncbi.nlm.nih.gov/books/NBK541057/. Date Accessed October 13, 2026.