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What Is Lipitor?

Lipitor is a prescription statin containing atorvastatin calcium. Current tablets contain 10 mg, 20 mg, 40 mg, or 80 mg of atorvastatin. It is used to reduce selected cardiovascular risks and to lower low-density lipoprotein cholesterol in adults and qualifying pediatric patients with lipid disorders.

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What Is Lipitor?

Lipitor is a prescription statin containing atorvastatin calcium. Current tablets contain 10 mg, 20 mg, 40 mg, or 80 mg of atorvastatin. It is used to reduce selected cardiovascular risks and to lower low-density lipoprotein cholesterol in adults and qualifying pediatric patients with lipid disorders.

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How Does Lipitor Lower Cholesterol?

Atorvastatin competitively inhibits HMG-CoA reductase, an enzyme involved in cholesterol synthesis in the liver. Lower hepatic cholesterol increases low-density lipoprotein receptor activity and clearance of low-density lipoprotein cholesterol from the blood.

Who Is Treated With Lipitor?

Lipitor is used in adults to reduce selected risks of heart attack, stroke, revascularization, and angina and to treat primary hyperlipidemia, hypertriglyceridemia, and primary dysbetalipoproteinemia. It is also used from age 10 for heterozygous or homozygous familial hypercholesterolemia under current labeling.

How Is Lipitor Dosed?

Adults usually start at 10 mg to 20 mg once daily, with a dosage range of 10 mg to 80 mg once daily. Adults who need a low-density lipoprotein cholesterol reduction greater than 45 percent can start at 40 mg once daily. Pediatric patients age 10 and older with heterozygous familial hypercholesterolemia start at 10 mg daily and use a range of 10 mg to 20 mg daily.

What Serious Risks Are Linked to Lipitor?

Serious concerns include myopathy and rhabdomyolysis, immune-mediated necrotizing myopathy, and hepatic dysfunction. Statins can also increase blood glucose and hemoglobin A1c. The 80 mg dose has been associated with increased hemorrhagic stroke risk in patients with a recent hemorrhagic stroke.

Frequently Asked Questions About Lipitor

What is Lipitor used for?

Lipitor reduces selected cardiovascular risks and treats several disorders involving elevated cholesterol or triglycerides.

What is the usual adult starting dose?

The recommended adult starting dose is 10 mg to 20 mg once daily.

What is the maximum adult dose?

The maximum recommended adult dose is 80 mg once daily.

Can children take Lipitor?

Yes. Current labeling includes patients age 10 and older with heterozygous or homozygous familial hypercholesterolemia.

References

Atorvastatin. LiverTox. https://www.ncbi.nlm.nih.gov/books/NBK548236/. Date Accessed October 13, 2026.

Atorvastatin. MedlinePlus. https://www.medlineplus.gov/druginfo/meds/a600045.html. Date Accessed October 13, 2026.

Atorvastatin. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Atorvastatin. Date Accessed October 13, 2026.

Atorvastatin. StatPearls. https://www.ncbi.nlm.nih.gov/books/NBK430779/. Date Accessed October 13, 2026.

DailyMed - LIPITOR (atorvastatin calcium) tablet, film coated. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a60cc18b-0631-4cf0-b021-9f52224ece65. Date Accessed October 13, 2026.