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Inderal is a propranolol trade name. The original immediate-release Inderal tablets and oral suspension are discontinued in the United States, while current extended-release products include Inderal LA and Inderal XL. Propranolol is a nonselective beta-adrenergic blocker.
read more about inderal ...Propranolol blocks beta-1 and beta-2 adrenergic receptors. This reduces heart rate, cardiac contractility, and renin release. Its exact mechanism in migraine prevention is not established.
Inderal LA is indicated for hypertension, angina pectoris due to coronary atherosclerosis, migraine prevention, and symptomatic hypertrophic subaortic stenosis. Inderal XL is indicated for hypertension. The extended-release products have distinct dosing instructions and are not treated as direct milligram-for-milligram substitutes for immediate-release propranolol.
Inderal LA hypertension treatment usually starts at 80 mg once daily, with maintenance dosing commonly ranging from 120 mg to 160 mg once daily. Angina treatment also starts at 80 mg once daily. Migraine prevention starts at 80 mg once daily, with a usual dose range of 160 mg to 240 mg once daily.
Abrupt discontinuation can worsen angina and has been associated with myocardial infarction in patients with coronary disease. Other concerns include slow heart rate, heart block, heart failure, bronchospasm, and low blood glucose. Cardiogenic shock, sinus bradycardia, greater than first-degree heart block, and bronchial asthma are contraindications for Inderal LA.
Inderal products contain propranolol hydrochloride, a nonselective beta-adrenergic blocker.
No. FDA lists the original immediate-release Inderal tablets and oral suspension as discontinued products.
The usual starting dose is 80 mg once daily.
No. Inderal LA is labeled for migraine prevention rather than treatment of an attack that has already begun.
Approved Drug Products With Therapeutic Equivalence Evaluations 46th Edition. https://www.fda.gov/media/71474/download. Date Accessed October 2, 2026.
DailyMed - INDERAL LA - propranolol hydrochloride capsule, extended release. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=35d28979-36b1-4630-b85e-a44e0a443734. Date Accessed October 2, 2026.
DailyMed - INDERAL XL - propranolol hydrochloride capsule, extended release. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ac196ff5-9215-402b-bc57-69aa87f8bade. Date Accessed October 2, 2026.
Propranolol - MedlinePlus Drug Information. https://medlineplus.gov/druginfo/meds/a682607.html. Date Accessed October 2, 2026.
Propranolol - StatPearls. https://www.ncbi.nlm.nih.gov/books/NBK557801/. Date Accessed October 2, 2026.