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Ibandronate sodium is a prescription bisphosphonate used for treatment and prevention of osteoporosis in postmenopausal women. Current oral tablets contain 150 mg and are taken once each month. Treatment increases bone mineral density and reduces vertebral fracture incidence.
read more about ibandronate ...Ibandronate has affinity for hydroxyapatite in the mineral matrix of bone. It inhibits osteoclast activity and reduces bone resorption and bone turnover. In postmenopausal osteoporosis, this shifts bone remodeling toward a net gain in bone mass.
Ibandronate tablets are used in postmenopausal women for osteoporosis treatment or prevention. Safety and efficacy in pediatric patients are not established. Continued bisphosphonate treatment is reassessed periodically, especially in patients with a lower fracture risk after several years of therapy.
The dose is one 150 mg tablet once monthly on the same date each month. It is taken after an overnight fast at least 60 minutes before the first food, drink other than plain water, medicine, or supplement of the day. The tablet is swallowed whole with 6 to 8 ounces of plain water while sitting or standing upright.
Serious concerns include esophageal irritation or ulceration, hypocalcemia, severe musculoskeletal pain, jaw osteonecrosis, atypical femur fractures, and kidney-related accumulation. Esophageal emptying disorders, inability to remain upright for at least 60 minutes, hypocalcemia, and hypersensitivity are contraindications. Severe kidney impairment is a reason to avoid treatment.
Ibandronate treats and prevents osteoporosis in postmenopausal women.
The current tablet dose is 150 mg once monthly on the same date each month.
The patient remains sitting or standing upright for at least 60 minutes after taking the tablet.
Yes. Jaw osteonecrosis and atypical femur fractures are recognized bisphosphonate risks.
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