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What Is Hyphema?

Hyphema is bleeding inside the front chamber of the eye, the space between the cornea and iris. It most often follows trauma, although medical conditions and recent eye surgery can also be involved. Even a small amount of blood can raise eye pressure and threaten vision, which is why prompt assessment is recommended.

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What Is Hyphema?

Hyphema is bleeding inside the front chamber of the eye, the space between the cornea and iris. It most often follows trauma, although medical conditions and recent eye surgery can also be involved. Even a small amount of blood can raise eye pressure and threaten vision, which is why prompt assessment is recommended.

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What Does Hyphema Look Like?

To the naked eye, hyphema appears as a red fluid level at the bottom of the pupil area. Eye doctors assess it at the slit lamp, grading how much of the anterior chamber is filled, from tiny suspended cells to a complete, dark "8-ball" fill. Photos online often show a clear line where blood has layered. If the bleed is microscopic, only an exam will detect it.

What Causes Hyphema?

Most cases start with a blunt injury that tears small vessels in the iris or ciliary body. Less common triggers include penetrating trauma, inflammatory eye disease, new abnormal blood vessels on the iris, clotting disorders, or a recent operation inside the eye. People with sickle cell disease or trait are at higher risk for pressure spikes and need tailored care.

What Are The Symptoms Of Hyphema?

Common symptoms are eye pain, blurred vision, light sensitivity, and seeing a reddish tinge or obvious blood in the eye. Some people experience nausea, vomiting, or headaches when eye pressure increases. Any of these symptoms after an eye injury warrants urgent evaluation, since the highest risk period for rebleeding is in the first several days.

Is What Is Hyphema Worth Worrying About?

Yes. Complications such as glaucoma, corneal blood staining, and rebleeding can threaten sight. Reported rebleeding rates are often listed as 5 to 10 percent and tend to occur within the first 3 to 5 days. Early diagnosis, activity limits, protective shielding, and appropriate medications help protect vision while the eye heals.

References

Cleveland Clinic. Hyphema overview. https://my.clevelandclinic.org/health/diseases/22586-hyphema

AAO EyeWiki. Hyphema. https://eyewiki.org/Hyphema

StatPearls. Hyphema. https://www.ncbi.nlm.nih.gov/books/NBK507802/

Chen EJ, et al. Management of Traumatic Hyphema and Prevention of Its Complications. 2021. https://pmc.ncbi.nlm.nih.gov/articles/PMC8291460/

AAO. YO Info: 5 Pearls for Managing Hyphema. https://www.aao.org/young-ophthalmologists/yo-info/article/yo-need-to-know-5-pearls-managing-hyphema

Cochrane Review. Medical treatment for traumatic hyphema. 2023. https://www.cochrane.org/evidence/CD005431_medical-treatment-traumatic-hyphema

FDA Orphan Designation. Aminocaproic acid for traumatic hyphema. https://www.accessdata.fda.gov/scripts/opdlisting/oopd/detailedIndex.cfm?cfgridkey=83294

Mayo Clinic Proceedings. Ophthalmic emergencies for the clinician. 2020. https://www.mayoclinicproceedings.org/article/S0025-6196%2820%2930304-9/fulltext

Frequently Asked Questions

How Is Hyphema Diagnosed And Treated?

Diagnosis is made with a slit-lamp exam and a pressure check. If there is concern for an open globe or internal damage, imaging may be considered. Initial care focuses on protecting the eye with a shield, resting with the head elevated, and avoiding strenuous activity.

As for the treatment, doctors often prescribe cycloplegic drops to rest the iris and topical steroids to calm inflammation. Pressure-lowering medications are used if needed, and patients are told to avoid aspirin and nonsteroidal pain relievers unless directed. Surgery to wash out the blood is considered when a large hyphema does not clear, pressure stays too high, or the cornea begins to stain.

Can Hyphema Cause Blindness?

Yes. Problems like uncontrolled pressure, corneal blood staining, or severe associated trauma can lead to permanent vision loss without timely care.

Do Hyphemas Cause Headaches?

They can. Headache, nausea, or vomiting may occur when eye pressure climbs and should prompt urgent reassessment.

Is Hyphema An Emergency?

Yes. It needs prompt ophthalmic evaluation and close follow-up during the first week to detect rebleeding or pressure spikes.