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Hodgkin Lymphoma (formerly Hodgkin's disease) is a type of cancer that begins in the lymphocytes (white blood cells) within the lymphatic system. The lymphatic system is a network of tissues and organs that help the body fight infection.
read more about hodgkin lymphoma ...The disease mechanism is defined by the presence of large, abnormal cancerous cells called Reed-Sternberg cells. These cells proliferate and crowd out healthy cells, disrupting the normal function of the immune system.
Painless lymph node swelling appears in the neck, armpits, or groin. Persistent fever, drenching night sweats, and unintended weight loss are classic systemic signs. Itching and fatigue can develop as the disease advances. Chest pressure or cough may occur if enlarged nodes press on airways. Symptoms warrant evaluation with exam, imaging, and biopsy.
Diagnosis typically requires a lymph node biopsy, where tissue is removed and examined under a microscope to confirm the presence of Reed-Sternberg cells. Imaging tests (CT and PET scans) are used for staging the cancer's spread.
Hodgkin lymphoma rarely impacts vision, but the cancer can infiltrate the orbital tissues or the retina, causing localized swelling, pain, or visual disturbances. More commonly, the intensive chemotherapy and radiation treatments can cause chronic dry eye or cataracts.
Treatment involves chemotherapy and often radiation therapy. Hodgkin Lymphoma is highly treatable, and the majority of patients achieve a cure or long-term remission.
No, Hodgkin Lymphoma is one of the less common cancers of the lymphatic system.
Hodgkin Lymphoma is distinguished by the presence of Reed-Sternberg cells, while Non-Hodgkin encompasses all other types.
Hodgkin Lymphoma is rare in children but common in two age groups: young adults (20s) and older adults (55+).
Consult a doctor for the "Alcohol Pain" sign, unexplained pain in your lymph nodes after drinking even a small amount of alcohol. This is a rare but highly specific symptom of Hodgkin Lymphoma. Also, watch for "B symptoms" like drenching night sweats and fever.
National Cancer Institute. Adult Hodgkin Treatment (cancer.gov). 2025.
American Cancer Society. Hodgkin Lymphoma (cancer.org). 2025.
Mayo Clinic. Hodgkin Symptoms (mayoclinic.org). 2025.
NHS. Hodgkin Lymphoma Overview (nhs.uk). 2025.