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What Is Glucagon?

Glucagon is a hormone that raises blood sugar by prompting the liver to release stored glucose. Medicines containing glucagon are used as emergency treatment for severe low blood sugar. Rescue products include injectable and nasal forms with different instructions.

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What Is Glucagon?

Glucagon is a hormone that raises blood sugar by prompting the liver to release stored glucose. Medicines containing glucagon are used as emergency treatment for severe low blood sugar. Rescue products include injectable and nasal forms with different instructions.

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What Is Glucagon Used For?

Glucagon rescue medicine is used when severe low blood sugar leaves someone unable to safely take sugar by mouth or needing help from another person. Certain injectable glucagon products are also used by healthcare professionals during digestive tract imaging. The prescribed product determines its approved use and age range.

How Does Glucagon Work?

Glucagon signals the liver to release stored glucose into the bloodstream. This raises blood sugar during a severe hypoglycemia emergency. Its response can be limited if the liver has too little stored glucose.

How Is Glucagon Given?

A trained family member or caregiver can give the prescribed rescue product according to its instructions. Some products are injected, while a nasal product is given into a nostril. Call for emergency medical help after giving glucagon, and provide oral sugar when the person is awake and able to swallow safely.

What Are the Risks of Glucagon?

Nausea and vomiting can occur after glucagon is given. Place an unconscious person on their side to reduce choking risk if vomiting occurs. Certain rare tumors, including insulinoma and pheochromocytoma, can make glucagon unsuitable, so the prescriber should review the patient's history.

Frequently Asked Questions About Glucagon

Is glucagon the same as insulin?

No. Glucagon raises blood sugar, while insulin lowers it.

Can glucagon be given to an unconscious person?

Yes. A trained caregiver can give a prescribed rescue product and should call for emergency medical help.

Should food or drink be given to an unconscious person?

No. Wait until the person is awake and can swallow safely before giving oral sugar or food.

Does glucagon come as a nasal medicine?

Yes. A nasal glucagon product is available, along with several injectable products.

References

Glucagon. StatPearls (NCBI Bookshelf). https://www.ncbi.nlm.nih.gov/books/NBK559195/. Date Accessed October 6, 2026.

Glucagon (injection route) - Side effects & dosage. Mayo Clinic. https://www.mayoclinic.org/drugs-supplements/glucagon-injection-route/description/drg-20064089. Date Accessed October 6, 2026.

Glucagon Injection. MedlinePlus. https://medlineplus.gov/druginfo/meds/a682480.html. Date Accessed October 6, 2026.

Glucagon Injection: Uses & Side Effects. Cleveland Clinic. https://my.clevelandclinic.org/health/drugs/20287-glucagon-injection. Date Accessed October 6, 2026.

Physiology, Glucagon. StatPearls (NCBI Bookshelf). https://www.ncbi.nlm.nih.gov/books/NBK537082/. Date Accessed October 6, 2026.