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What Is Genvoya?

Genvoya is a prescription tablet containing elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide. It is a complete treatment regimen for HIV-1 in eligible adults and children who weigh at least 25 kg. It controls the virus but does not cure HIV.

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What Is Genvoya?

Genvoya is a prescription tablet containing elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide. It is a complete treatment regimen for HIV-1 in eligible adults and children who weigh at least 25 kg. It controls the virus but does not cure HIV.

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What Is Genvoya Used For?

Genvoya can be prescribed to eligible people starting HIV treatment. It can also replace a stable regimen for certain people whose virus has remained suppressed and who meet the label criteria. A clinician reviews treatment history, resistance, and other health conditions before prescribing it.

How Does Genvoya Work?

Elvitegravir blocks an HIV enzyme called integrase. Emtricitabine and tenofovir alafenamide interfere with another enzyme the virus needs to copy itself. Cobicistat raises elvitegravir levels so it can work as part of the once-daily tablet.

How Is Genvoya Taken?

Take one tablet by mouth once daily with food. Taking it regularly helps keep HIV suppressed and reduces the chance of drug resistance. The care team checks kidney function and reviews other medicines for interactions.

What Are the Risks of Genvoya?

Genvoya can interact with prescription drugs, over-the-counter medicines, and herbal products. Kidney problems can occur, so monitoring is part of treatment. Stopping Genvoya can cause a serious hepatitis B flare in people who have both HIV and hepatitis B.

Frequently Asked Questions About Genvoya

Does Genvoya cure HIV?

No. It suppresses HIV when taken as prescribed but does not eliminate the infection.

Should Genvoya be taken with food?

Yes. Take the tablet once daily with food.

Is Genvoya taken with other HIV medicines?

Genvoya is designed as a complete HIV treatment regimen. Do not add or stop HIV medicines without guidance from the prescriber.

Why is hepatitis B testing needed?

People with HIV can also have hepatitis B. If both infections are present, stopping Genvoya can trigger a serious hepatitis B flare.

References

Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide (AF). MedlinePlus. https://medlineplus.gov/druginfo/meds/a625076.html. Date Accessed October 6, 2026.

Elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide (oral route) - Side effects & dosage. Mayo Clinic. https://www.mayoclinic.org/drugs-supplements/elvitegravir-cobicistat-emtricitabine-and-tenofovir-alafenamide-oral-route/description/drg-20165161. Date Accessed October 6, 2026.

Genvoya FDA Label. NIH HIVinfo. https://clinicalinfo.hiv.gov/en/drugs/elvitegravir-cobicistat-emtricitabine-tenofovir-alafenamide/fda-label. Date Accessed October 6, 2026.

Genvoya Patient Drug Record. NIH HIVinfo. https://clinicalinfo.hiv.gov/en/drugs/elvitegravir-cobicistat-emtricitabine-tenofovir-alafenamide/patient. Date Accessed October 6, 2026.

GENVOYA- elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide tablet. DailyMed (National Library of Medicine). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=34784acf-15ed-4715-b504-eb30430518e9. Date Accessed October 6, 2026.