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Gemfibrozil is a prescription medicine in the fibrate class. It is used to improve certain abnormal blood fat levels, particularly high triglycerides. Treatment is paired with dietary and other measures recommended by a clinician.
read more about gemfibrozil ...Gemfibrozil lowers triglycerides and can raise HDL cholesterol. A clinician may prescribe it for patients with marked triglyceride elevations or certain other lipid disorders. Blood tests help assess whether levels are responding to treatment.
Gemfibrozil changes how the body processes fats in the blood. It reduces triglyceride production in the liver and helps lower circulating triglycerides. Its effect is monitored with follow-up lipid tests.
Gemfibrozil comes as a tablet taken by mouth. It is usually taken twice daily, 30 minutes before the morning and evening meals. Take it as prescribed and continue the recommended diet and activity plan.
Stomach pain or heartburn can occur. Unexplained muscle pain, tenderness, or weakness needs prompt medical attention, particularly when other cholesterol medicines are involved. Tell the prescriber about all medicines and any liver, kidney, or gallbladder disease before treatment.
It is usually taken 30 minutes before breakfast and the evening meal. Follow the directions on your prescription.
No. Dietary changes and exercise remain part of the treatment plan.
Yes. Some combinations increase the risk of serious muscle injury, so a clinician should review all current medicines.
Contact the prescriber promptly for unexplained muscle pain, tenderness, or weakness. They can assess whether treatment needs to change.
Fibrates. MedlinePlus. https://www.medlineplus.gov/ency/patientinstructions/000789.htm. Date Accessed October 6, 2026.
Gemfibrozil. MedlinePlus. https://medlineplus.gov/druginfo/meds/a686002.html. Date Accessed October 6, 2026.
Gemfibrozil. StatPearls (NCBI Bookshelf). https://www.ncbi.nlm.nih.gov/books/NBK545266/. Date Accessed October 6, 2026.
Gemfibrozil (oral route) - Side effects & dosage. Mayo Clinic. https://www.mayoclinic.org/drugs-supplements/gemfibrozil-oral-route/description/drg-20064018. Date Accessed October 6, 2026.
Gemfibrozil tablets. Cleveland Clinic. https://my.clevelandclinic.org/health/drugs/18002-gemfibrozil-tablets. Date Accessed October 6, 2026.