What Is Gattex?
Gattex is the brand name for teduglutide, a prescription medicine for short bowel syndrome. It is a glucagon-like peptide-2 analog. It is given as a daily injection under the skin.
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What Is Gattex Used For?
Gattex treats adults and children aged 1 year and older with short bowel syndrome who depend on intravenous nutrition or fluids. Treatment can improve intestinal absorption and reduce the amount of intravenous support some people need. The care team adjusts that support based on the individual response.
How Does Gattex Work?
Teduglutide acts like the intestinal hormone glucagon-like peptide-2. It promotes changes in the intestinal lining that can improve the absorption of fluids and nutrients. It does not restore the missing section of bowel.
How Is Gattex Given?
Gattex is injected under the skin once daily after its powder is mixed as directed. Injection sites can include the abdomen, thigh, or upper arm and should be rotated. The dose is based on body weight and may need adjustment for reduced kidney function.
What Are Gattex Side Effects and Precautions?
Abdominal pain, nausea, and injection-site reactions can occur. Gattex can increase the growth of abnormal tissue, so bowel screening is required before and during treatment. The care team also monitors for bowel blockage, gallbladder or pancreatic problems, and fluid overload.
Frequently Asked Questions About Gattex
Does Gattex replace intravenous nutrition or fluids?
Some people need less intravenous support during treatment, but results vary. The care team decides when any change is appropriate.
Can children use Gattex?
Yes. It is indicated for eligible children aged 1 year and older who depend on parenteral support.
Why are bowel examinations needed with Gattex?
The medicine can promote the growth of abnormal tissue, including polyps. Screening helps detect changes before and during treatment.
Is Gattex injected into a vein?
No. It is injected under the skin, not into a vein or muscle.
References
GATTEX (teduglutide) for injection: Prescribing Information. DailyMed (National Library of Medicine). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=66b69c1e-b25c-44d3-b5ff-1c1de9a516fa. Date Accessed October 6, 2026.
GATTEX? Adult Patient Safety Information for Your Practice. Takeda. https://www.gattexhcp.com/adult-safety. Date Accessed October 6, 2026.
Teduglutide (subcutaneous route) - Side effects & dosage. Mayo Clinic. https://www.mayoclinic.org/drugs-supplements/teduglutide-subcutaneous-route/description/drg-20060737. Date Accessed October 6, 2026.
Teduglutide Injection. MedlinePlus. https://medlineplus.gov/druginfo/meds/a613019.html. Date Accessed October 6, 2026.
Teduglutide Injection: Uses & Side Effects. Cleveland Clinic. https://my.clevelandclinic.org/health/drugs/20124-teduglutide-injection. Date Accessed October 6, 2026.