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What Is Fosfomycin?

Fosfomycin is an antibiotic that kills susceptible bacteria. An oral form is supplied as granules that are mixed with water. An injectable form is used for different infections under medical supervision.

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What Is Fosfomycin?

Fosfomycin is an antibiotic that kills susceptible bacteria. An oral form is supplied as granules that are mixed with water. An injectable form is used for different infections under medical supervision.

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What Is Fosfomycin Used For?

Oral fosfomycin treats uncomplicated bladder infections in adult women caused by susceptible bacteria. It is not indicated for kidney infections. Injectable fosfomycin has a separate role in treating certain complicated urinary tract infections.

How Does Fosfomycin Work?

Fosfomycin blocks an early step in building bacterial cell walls. Without a working cell wall, susceptible bacteria cannot survive. It does not treat viral infections.

How Is Fosfomycin Taken?

For an uncomplicated bladder infection, oral fosfomycin is generally prescribed as a single packet taken once. Mix the entire packet with cold water and drink it soon after preparation. Do not swallow the dry granules or take extra doses unless instructed by a clinician.

What Are Fosfomycin Side Effects and Precautions?

Nausea, diarrhea, headache, and vaginal itching can occur after oral treatment. Seek medical advice for an allergic reaction or severe watery diarrhea. Contact the prescriber if urinary symptoms do not improve within two to three days or if fever or flank pain develops.

Frequently Asked Questions About Fosfomycin

Is oral fosfomycin a one-dose treatment?

For its approved uncomplicated bladder infection use, it is taken as one mixed packet. Do not repeat the dose unless the prescriber directs you to.

Can oral fosfomycin treat a kidney infection?

No. The oral packet is not indicated for a kidney infection.

Can I swallow fosfomycin granules dry?

No. Mix the full packet with cold water and drink it after stirring.

When should bladder symptoms improve?

Improvement is expected within two to three days. Contact the prescriber if symptoms persist or worsen.

References

Fosfomycin. MedlinePlus. https://medlineplus.gov/druginfo/meds/a697008.html. Date Accessed October 6, 2026.

Fosfomycin (intravenous route) - Side effects & uses. Mayo Clinic. https://www.mayoclinic.org/drugs-supplements/fosfomycin-intravenous-route/description/drg-80008541. Date Accessed October 6, 2026.

Fosfomycin (oral route) - Side effects & dosage. Mayo Clinic. https://www.mayoclinic.org/drugs-supplements/fosfomycin-oral-route/description/drg-20063920. Date Accessed October 6, 2026.

Fosfomycin Injection. MedlinePlus. https://www.medlineplus.gov/druginfo/meds/a625118.html. Date Accessed October 6, 2026.

Urinary tract infection (UTI) - Diagnosis and treatment. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/urinary-tract-infection/diagnosis-treatment/drc-20353453. Date Accessed October 6, 2026.