What Is Fosamax?
Fosamax is a brand name for alendronate, a medicine in the bisphosphonate class. It slows the breakdown of bone. It is taken by mouth for certain bone conditions.
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What Is Fosamax Used For?
Fosamax treats osteoporosis in postmenopausal women and men. It can also be used to prevent osteoporosis in postmenopausal women and to treat certain cases of osteoporosis linked to glucocorticoid use. Another approved use is Paget disease of bone.
How Does Fosamax Work?
Bone is continually broken down and rebuilt. Alendronate reduces the activity of cells that break down bone. This can improve bone density and lower fracture risk in people treated for osteoporosis.
How Is Fosamax Taken?
Take Fosamax first thing in the morning with a full glass of plain water, before food or other medicines. Swallow the tablet whole and remain sitting or standing for at least 30 minutes. Wait at least 30 minutes before eating, drinking anything other than water, or taking other oral medicines.
What Are Fosamax Side Effects and Precautions?
Fosamax can irritate the esophagus, particularly if dosing instructions are not followed. Stomach discomfort and bone, joint, or muscle pain can also occur. Report trouble swallowing, new chest pain, jaw problems, or persistent thigh or groin pain.
Frequently Asked Questions About Fosamax
Why must I stay upright after taking Fosamax?
Remaining upright helps the tablet move into the stomach. This lowers the risk of esophageal irritation.
Can I take Fosamax with coffee?
No. Take it with plain water only, then wait at least 30 minutes before drinking coffee.
Is Fosamax taken every day?
The schedule depends on the prescribed strength and treatment plan. A common osteoporosis regimen is taken once weekly.
Can I take calcium at the same time as Fosamax?
No. Wait at least 30 minutes after Fosamax before taking calcium or other oral medicines.
References
Alendronate. MedlinePlus. https://www.medlineplus.gov/druginfo/meds/a601011.html. Date Accessed October 6, 2026.
Alendronate (oral route) - Side effects & dosage. Mayo Clinic. https://www.mayoclinic.org/drugs-supplements/alendronate-oral-route/description/drg-20061571. Date Accessed October 6, 2026.
Alendronate: Uses & Side Effects. Cleveland Clinic. https://my.clevelandclinic.org/health/drugs/20919-alendronate-tablets. Date Accessed October 6, 2026.
FOSAMAX- alendronate sodium tablet. DailyMed (National Library of Medicine). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=14e931fd-2c5f-4d90-b7db-5980706f4a56. Date Accessed October 6, 2026.
Medicines for osteoporosis. MedlinePlus. https://www.medlineplus.gov/ency/patientinstructions/000502.htm. Date Accessed October 6, 2026.