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What Is Fintepla?

Fintepla is the brand name for fenfluramine, a prescription seizure medicine. It treats seizures associated with Dravet syndrome or Lennox-Gastaut syndrome in patients ages 2 and older. It is an oral liquid used under a restricted safety program due to risks involving the heart valves and blood pressure in the lungs.

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What Is Fintepla?

Fintepla is the brand name for fenfluramine, a prescription seizure medicine. It treats seizures associated with Dravet syndrome or Lennox-Gastaut syndrome in patients ages 2 and older. It is an oral liquid used under a restricted safety program due to risks involving the heart valves and blood pressure in the lungs.

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What Is Fintepla Used For?

Fintepla is used to reduce seizures associated with Dravet syndrome and Lennox-Gastaut syndrome. These are forms of epilepsy that can begin in childhood. The treating clinician selects the dose based on the condition, body weight, and other medicines.

How Does Fintepla Work?

The exact way fenfluramine reduces seizures is unknown. It affects signaling involving serotonin in the nervous system. Its effect on serotonin receptors is also linked to the need for heart monitoring.

How Is Fintepla Taken?

Fintepla is an oral solution taken according to a prescribed schedule. Patients need an echocardiogram before treatment, every six months during treatment, and again after the final dose. It is supplied through the Fintepla Risk Evaluation and Mitigation Strategy program.

What Are the Side Effects and Precautions?

Reduced appetite, weight loss, sleepiness, diarrhea, and fatigue can occur. Fintepla can cause heart valve disease or pulmonary arterial hypertension. A clinician also monitors mood, blood pressure, and other possible effects during treatment.

Frequently Asked Questions About Fintepla

What conditions does Fintepla treat?

It treats seizures associated with Dravet syndrome and Lennox-Gastaut syndrome. Its U.S. approval covers patients ages 2 and older.

Why are echocardiograms required?

They check for heart valve problems and signs of high blood pressure in the lung arteries. Testing is required before, during, and after treatment.

Is Fintepla a liquid?

Yes. It is supplied as an oral solution. Use the measuring device and instructions provided with the medicine.

Can Fintepla be stopped suddenly?

Do not stop it without guidance from the treating clinician. Antiseizure medicines are usually reduced gradually to lower the risk of worsening seizures.

References

Fenfluramine. MedlinePlus. https://www.medlineplus.gov/druginfo/meds/a620045.html. Date Accessed October 6, 2026.

Fenfluramine (oral route) - Side effects & dosage. Mayo Clinic. https://www.mayoclinic.org/drugs-supplements/fenfluramine-oral-route/description/drg-20490822. Date Accessed October 6, 2026.

Fintepla. UCB. https://www.ucb-usa.com/Innovation/Products/Fintepla. Date Accessed October 6, 2026.

FINTEPLA- fenfluramine solution. DailyMed (National Library of Medicine). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e88f360e-33ad-4cd6-b2de-5ef885857c5d. Date Accessed October 6, 2026.

FINTEPLA? (fenfluramine). UCB. https://www.fintepla.com/. Date Accessed October 6, 2026.