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Finerenone is a prescription medicine sold under the brand name Kerendia. It blocks mineralocorticoid receptors involved in kidney and heart damage. Its approved uses include certain adults with chronic kidney disease linked to diabetes and adults with a specified type of heart failure.
read more about finerenone ...In adults with chronic kidney disease linked to type 2 diabetes, finerenone reduces several kidney and cardiovascular risks. For chronic kidney disease linked to type 1 diabetes, its approved use is to reduce urine albumin, a change expected to lower the risk of kidney disease progression. It also reduces certain cardiovascular risks in adults with heart failure and a left ventricular ejection fraction of at least 40%.
Finerenone blocks the effects of the hormone aldosterone at mineralocorticoid receptors. This helps limit processes that contribute to inflammation and scarring in the kidneys and heart. It can also raise potassium levels in the blood.
Finerenone is a tablet taken once daily, with or without food. The starting dose depends on kidney function and blood potassium levels. A clinician repeats these tests after treatment begins and adjusts the dose as needed.
High blood potassium is a major risk, especially when kidney function is reduced. Low blood pressure and low blood sodium can also occur. Tell a clinician about other medicines and supplements, and avoid grapefruit unless the prescribing team says otherwise.
Yes, under its September 2026 U.S. labeling for certain adults. That indication is based on reducing urine albumin, which is expected to reduce the risk of kidney disease progression.
Yes, if they meet the approved heart failure criteria. The heart failure indication does not require diabetes.
Finerenone can raise potassium to unsafe levels. Testing guides the starting dose and later adjustments.
Avoid grapefruit and grapefruit juice during treatment. They can increase finerenone levels in the blood.
Bayer's KERENDIA FDA Approval. Bayer. https://www.bayer.com/en-us/united-states/news-and-stories/2026/treatment-forchronic-kidney-disease-and-type-1-diabetes. Date Accessed October 6, 2026.
Finerenone. MedlinePlus. https://medlineplus.gov/druginfo/meds/a621038.html. Date Accessed October 6, 2026.
Finerenone (oral route) - Side effects & dosage. Mayo Clinic. https://www.mayoclinic.org/drugs-supplements/finerenone-oral-route/description/drg-20518736. Date Accessed October 6, 2026.
Finerenone Oral Tablets. Cleveland Clinic. https://my.clevelandclinic.org/health/drugs/23598-finerenone-oral-tablets. Date Accessed October 6, 2026.
KERENDIA (finerenone) tablets: Prescribing Information. Bayer. https://labeling.bayerhealthcare.com/html/products/pi/Kerendia_PI.pdf. Date Accessed October 6, 2026.