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Femara is the brand name for letrozole, a prescription breast cancer medicine. It belongs to a group called aromatase inhibitors. It lowers estrogen levels in postmenopausal women, which can slow the growth of certain breast cancers.
read more about femara ...Femara treats hormone receptor-positive early breast cancer after menopause. It is also used after a course of tamoxifen and for certain advanced breast cancers in postmenopausal women. The treatment plan depends on the cancer and previous therapy.
An enzyme called aromatase helps the body make estrogen after menopause. Letrozole blocks this enzyme and lowers estrogen levels. Breast cancers that rely on estrogen then receive less of the signal that supports their growth.
Femara is a tablet taken by mouth once daily, with or without food. Treatment can continue for years when it is used after surgery for early breast cancer. The cancer care team determines the duration and checks how treatment is going.
Hot flashes, joint pain, fatigue, and dizziness can occur. Femara can reduce bone mineral density, so bone health may need monitoring. It can harm a fetus and should not be used during pregnancy.
No. Femara is hormonal therapy that lowers estrogen production. It works differently from traditional chemotherapy medicines.
Its approved breast cancer uses are for postmenopausal women. A clinician assesses menopausal status when planning treatment.
Yes. Lower estrogen levels can reduce bone mineral density and increase fracture risk. The care team may monitor bone health during treatment.
Yes. The tablet can be taken with or without a meal.
Definition of letrozole - NCI Drug Dictionary. National Cancer Institute. https://www.cancer.gov/publications/dictionaries/cancer-drug/def/letrozole. Date Accessed October 6, 2026.
Letrozole. MedlinePlus. https://medlineplus.gov/druginfo/meds/a698004.html. Date Accessed October 6, 2026.
Letrozole. National Cancer Institute. https://www.cancer.gov/about-cancer/treatment/drugs/letrozole. Date Accessed October 6, 2026.
Letrozole (oral route) - Side effects & dosage. Mayo Clinic. https://www.mayoclinic.org/drugs-supplements/letrozole-oral-route/description/drg-20067579. Date Accessed October 6, 2026.
LETROZOLE tablet, film coated. DailyMed (National Library of Medicine). https://www.dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c391fe11-fd47-4a35-af6d-c823ab7b8838. Date Accessed October 6, 2026.