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Desloratadine is a prescription histamine H1 receptor antagonist used for allergic conditions. Current 5 mg tablets treat seasonal allergic rhinitis, perennial allergic rhinitis, and chronic idiopathic urticaria in patients age 12 and older. Oral liquid formulations extend selected indications to younger children under age-specific dosing.
read more about desloratadine ...Desloratadine is a long-acting tricyclic antihistamine with selective activity at peripheral H1 receptors. Blocking histamine at these receptors reduces symptoms such as sneezing, runny nose, nasal itching, watery eyes, itching, and hives. Desloratadine also inhibits histamine release from human mast cells in laboratory studies.
Desloratadine treats seasonal and perennial allergic rhinitis and chronic idiopathic urticaria. The 5 mg tablet is labeled from age 12. Current oral liquid labeling covers seasonal allergic rhinitis from age 2 and perennial allergic rhinitis and chronic idiopathic urticaria from age 6 months.
Adults and adolescents age 12 and older take 5 mg once daily with or without food. Oral liquid dosing is 2.5 mg once daily for ages 6 to 11, 1.25 mg once daily for ages 1 to 5, and 1 mg once daily for ages 6 to 11 months. Adults with liver or kidney impairment start with 5 mg every other day.
Serious hypersensitivity reactions, including rash, itching, hives, swelling, breathing difficulty, and anaphylaxis, have been reported. Desloratadine is contraindicated in patients with hypersensitivity to desloratadine, loratadine, or product ingredients. Other reported reactions include dry mouth, fatigue, muscle pain, throat inflammation, and sleepiness.
Yes. Desloratadine is a long-acting histamine H1 receptor antagonist.
Adults and adolescents age 12 and older take one 5 mg tablet once daily.
Yes. It treats itching and hives associated with chronic idiopathic urticaria under age-specific labeling.
Yes. Adults with liver or kidney impairment start with 5 mg every other day under current tablet labeling.
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DailyMed - DESLORATADINE tablet. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4b546121-ef6b-458c-ae0c-ce5bba3dc9a3. Date Accessed September 24, 2026.
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