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Cyclobenzaprine is a prescription skeletal muscle relaxant used as an adjunct to rest and physical therapy for muscle spasm associated with acute, painful musculoskeletal conditions. Immediate-release tablets commonly come in 5 mg, 7.5 mg, and 10 mg strengths. Treatment is intended for short periods of up to two or three weeks.
read more about cyclobenzaprine ...Cyclobenzaprine acts mainly within the central nervous system and reduces skeletal muscle spasm of local origin without directly interfering with muscle function. Its exact mechanism in humans is not fully defined. It is not useful for spasticity caused by cerebral or spinal cord disease.
Cyclobenzaprine is used for short-term relief of muscle spasm linked to acute, painful musculoskeletal conditions. It is used alongside rest and physical therapy. Current tablet labeling does not recommend prolonged treatment beyond two or three weeks, since these conditions are generally short in duration.
Most adults start with 5 mg three times daily. Based on individual response, the dose can increase to 10 mg three times daily. Lower-frequency dosing is considered in older adults or people with liver impairment. Use beyond two or three weeks is not recommended under current tablet labeling.
Cyclobenzaprine can cause serotonin syndrome, drowsiness, dizziness, dry mouth, and anticholinergic effects. It is contraindicated with monoamine oxidase inhibitors or within 14 days after stopping them. It is also contraindicated during acute recovery after myocardial infarction and in patients with certain arrhythmias, heart block, congestive heart failure, or hyperthyroidism.
Cyclobenzaprine relieves muscle spasm associated with acute, painful musculoskeletal conditions when used with rest and physical therapy.
A common adult regimen starts at 5 mg three times daily.
Current tablet labeling recommends short-term use for up to two or three weeks.
Yes. Drowsiness is a common reaction and can be intensified by alcohol or other central nervous system depressants.
Cyclobenzaprine. LiverTox. https://www.ncbi.nlm.nih.gov/books/NBK548894/. Date Accessed September 24, 2026.
Cyclobenzaprine. MedlinePlus. https://medlineplus.gov/druginfo/meds/a682514.html. Date Accessed September 24, 2026.
Cyclobenzaprine. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Cyclobenzaprine. Date Accessed September 24, 2026.
Cyclobenzaprine. StatPearls. https://www.ncbi.nlm.nih.gov/books/NBK513362/. Date Accessed September 24, 2026.
DailyMed - CYCLOBENZAPRINE HYDROCHLORIDE tablet, film coated. https://www.dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=29ca9548-23b0-4c50-82cb-4f0564d7e065. Date Accessed September 24, 2026.