Provide a valuable resource to your clients or customers by linking to this resource page. Just place the following link on your website.
Brimonidine is an alpha-2 adrenergic agonist available in several U.S. formulations with different uses. Prescription ophthalmic drops lower elevated intraocular pressure in open-angle glaucoma or ocular hypertension. Brimonidine topical gel 0.33% treats persistent facial erythema of rosacea in adults. Lower-strength ophthalmic products also exist for eye redness, so directions depend on the exact formulation.
read more about brimonidine ...In the eye, brimonidine lowers intraocular pressure by reducing aqueous humor production and increasing uveoscleral outflow. On facial skin, topical brimonidine activates alpha-2 adrenergic receptors and constricts small blood vessels, reducing persistent redness from rosacea. These local actions differ by formulation, which is why ophthalmic drops and facial gel are not interchangeable.
Prescription brimonidine eye drops are used for elevated intraocular pressure in open-angle glaucoma or ocular hypertension. Brimonidine topical gel 0.33% is used for persistent facial erythema of rosacea in adults age 18 and older. Each formulation has its own concentration, route, age limits, and administration instructions.
Brimonidine 0.1% eye drops are instilled as one drop in the affected eye or eyes three times daily, about eight hours apart. Brimonidine topical gel 0.33% is applied once daily as a pea-sized amount to each of five facial areas, covering the forehead, chin, nose, and both cheeks while avoiding the eyes and lips.
Brimonidine eye drops are contraindicated in children younger than 2 and in people with prior hypersensitivity. Caution is advised with vascular insufficiency or severe cardiovascular disease. Topical gel can cause redness, flushing, burning, or contact dermatitis. Accidental swallowing of the gel, especially by a child, has caused serious systemic reactions requiring urgent medical care.
Yes. Prescription ophthalmic brimonidine lowers elevated intraocular pressure in people with open-angle glaucoma or ocular hypertension.
Yes. Brimonidine topical gel 0.33% treats persistent facial redness from rosacea in adults age 18 and older.
The labeled regimen is one drop in the affected eye or eyes three times daily, about eight hours apart.
Brimonidine eye drops are contraindicated in children younger than 2 years and used cautiously in older pediatric patients.
ALPHAGAN P (brimonidine tartrate ophthalmic solution) Prescribing Information. https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/021770s014%2C021262s028lbl.pdf. Date Accessed September 17, 2026.
Brimonidine Ophthalmic. MedlinePlus. https://www.medlineplus.gov/druginfo/meds/a601232.html. Date Accessed September 17, 2026.
DailyMed - BRIMONIDINE TARTRATE ophthalmic solution 0.1%. https://www.dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5a634ed6-f00a-472e-93c9-8dcd496997a2. Date Accessed September 17, 2026.
DailyMed - LUMIFY REDNESS RELIEVER EYE DROPS (brimonidine tartrate) solution/drops. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=022de945-0b26-40ae-8e88-d3fe2464d106. Date Accessed September 17, 2026.
DailyMed - MIRVASO (brimonidine tartrate) gel. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f6a4353f-ae69-4214-901f-e5d42a6fbde7. Date Accessed September 17, 2026.