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Aqueous humor leaves the eye through two main pathways: the trabecular pathway and the uveoscleral pathway. The trabecular route drains fluid through the trabecular meshwork and Schlemm's canal. The uveoscleral pathway allows fluid to pass through the ciliary body into surrounding tissues. Together, these pathways help regulate intraocular pressure.
read more about aqueous outflow ...Most aqueous humor exits through the trabecular pathway. A smaller portion leaves through the uveoscleral route. Changes in either pathway can affect pressure. Glaucoma treatments target these outflow systems.
The trabecular pathway is the primary route.
Yes, it handles a meaningful portion of drainage.
Yes, blockage can increase pressure.
Some medicines increase uveoscleral or trabecular outflow.
In the conventional (trabecular) pathway, aqueous humor drains through the trabecular meshwork into the Schlemm's canal and then into episcleral veins?294075165109692?L120-L128?.
In the uveoscleral pathway, aqueous humor flows through spaces within the ciliary muscle and out via the suprachoroidal space and sclera. This pathway accounts for a smaller portion of outflow.
Medications such as prostaglandin analogs increase uveoscleral outflow, while others like beta-blockers and carbonic anhydrase inhibitors reduce aqueous production. Laser and surgical procedures can also enhance trabecular outflow.