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Lidex was a trade name for fluocinonide 0.05 percent topical corticosteroid products. FDA records describe Lidex as discontinued, while generic fluocinonide 0.05 percent creams, gels, ointments, and solutions remain marketed in the United States.
read more about what was lidex ...Fluocinonide is a topical corticosteroid that activates glucocorticoid receptors and reduces inflammatory and immune activity in the skin. These actions reduce redness, swelling, and itching in corticosteroid-responsive dermatoses.
Lidex products were used for inflammatory and itchy skin conditions that respond to topical corticosteroids. Current generic fluocinonide 0.05 percent products retain this type of use. They are for external use and are not applied to the eyes.
Current generic 0.05 percent cream, gel, ointment, and related topical labeling directs a thin film to the affected area two to four times daily according to condition severity. Occlusive dressings are used only when directed by a clinician.
Systemic absorption can suppress the hypothalamic-pituitary-adrenal axis and cause Cushing syndrome, high blood glucose, or glucosuria. Prolonged use can thin the skin, and children are more susceptible to systemic corticosteroid effects. Local burning, itching, irritation, dryness, folliculitis, acne-like eruptions, and skin color changes can occur.
Lidex contained fluocinonide, a topical corticosteroid.
FDA records describe Lidex as discontinued, while generic fluocinonide topical products remain marketed.
Lidex topical products used fluocinonide 0.05 percent.
Current generic labeling commonly directs a thin film to affected skin two to four times daily.
DailyMed - FLUOCINONIDE cream. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=f5f39a14-005a-4124-9c00-500598e28012. Date Accessed October 13, 2026.
Determination That LIDEX (fluocinonide) Cream and LIDEX-E (fluocinonide) Cream and Nine Other Drug Products Were Not Withdrawn From Sale for Reasons of Safety or Effectiveness. U.S. Food and Drug Administration. https://public-inspection.federalregister.gov/2013-20086.pdf. Date Accessed October 13, 2026.
Fluocinonide. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Fluocinonide. Date Accessed October 13, 2026.
Fluocinonide Topical. MedlinePlus. https://www.medlineplus.gov/druginfo/meds/a601054.html. Date Accessed October 13, 2026.
Topical Corticosteroids. StatPearls. https://www.ncbi.nlm.nih.gov/books/NBK532940/. Date Accessed October 13, 2026.