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Hydrocortisone tablets are prescription glucocorticoids available in 5 mg, 10 mg, and 20 mg strengths. They are used as replacement therapy in adrenocortical deficiency states and for anti-inflammatory or immunosuppressive treatment across selected endocrine, rheumatic, allergic, dermatologic, ophthalmic, respiratory, hematologic, gastrointestinal, and other disorders.
read more about oral hydrocortisone ...Hydrocortisone is chemically identical to the principal glucocorticoid produced by the adrenal cortex. It has glucocorticoid and salt-retaining activity and replaces deficient corticosteroid activity in adrenal disorders. At pharmacologic doses, it also changes inflammatory and immune responses through glucocorticoid receptor signaling.
Current tablet labeling includes primary or secondary adrenocortical insufficiency, congenital adrenal hyperplasia, nonsuppurative thyroiditis, hypercalcemia associated with cancer, and selected inflammatory, allergic, autoimmune, blood, gastrointestinal, respiratory, and neoplastic conditions. The exact indication determines treatment length and dose.
Dosing is individualized according to the disease and clinical response. Current tablet labeling lists initial daily doses from 20 mg to 240 mg depending on the condition being treated. After a satisfactory response, the dose is reduced in small steps to the lowest dose that maintains the needed clinical response.
Systemic hydrocortisone suppresses immune activity and increases infection risk. Other concerns include adrenal suppression after prolonged therapy, high blood pressure, fluid retention, low potassium, high blood glucose, osteoporosis, cataracts, glaucoma, psychiatric effects, and gastrointestinal complications. Systemic fungal infection is a contraindication.
Hydrocortisone is a glucocorticoid used for corticosteroid replacement and treatment of selected inflammatory or immune-mediated disorders.
Current hydrocortisone tablets are available in 5 mg, 10 mg, and 20 mg strengths.
No. Dosing varies by the disease being treated and the individual clinical response.
Yes. Systemic corticosteroid treatment suppresses immune responses and can increase the risk or severity of infections.
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