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What Is Nilandron?

Nilandron is a brand name historically used for nilutamide, a prescription nonsteroidal antiandrogen medication. Nilutamide is indicated for metastatic prostate cancer when used with surgical castration. It blocks the effects of androgens on prostate cancer cells and is typically started at the time of surgery. Although brand availability can differ, nilutamide prescribing information remains relevant for understanding its approved use, dosing, and safety risks.

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What Is Nilandron?

Nilandron is a brand name historically used for nilutamide, a prescription nonsteroidal antiandrogen medication. Nilutamide is indicated for metastatic prostate cancer when used with surgical castration. It blocks the effects of androgens on prostate cancer cells and is typically started at the time of surgery. Although brand availability can differ, nilutamide prescribing information remains relevant for understanding its approved use, dosing, and safety risks.

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How Does Nilandron Work?

Nilandron contains nilutamide, an androgen receptor antagonist that blocks the effects of testosterone and related hormones on target tissues. Prostate cancer growth is often stimulated by androgen signaling. Surgical castration lowers testosterone production, while nilutamide blocks androgen receptor activity that can remain. This combination helps limit hormone-driven cancer growth. Nilutamide does not directly lower testosterone production and is not intended to replace surgical castration.

Who Is Nilandron Prescribed For?

Nilandron is indicated for patients with metastatic prostate cancer who have undergone surgical castration. It is used as part of combined androgen blockade to reduce the effects of male hormones on cancer cells. Treatment begins on the day of surgery or the following day. Nilutamide is not indicated for women or for unrelated hormonal conditions. An oncology specialist considers respiratory health, liver function, disease status, and treatment risks before prescribing it.

How Should Nilandron Be Taken?

The recommended nilutamide dosage is 300 mg orally once daily for the first 30 days, followed by 150 mg once daily. Tablets can be taken with or without food. Treatment is started on the day of surgical castration or the following day. Patients should take the medication according to their oncology treatment plan and should not interrupt therapy without consulting their clinician. Regular follow-up is necessary to monitor cancer response and adverse effects.

What Are the Side Effects and Warnings of Nilandron?

Nilutamide can cause hot flashes, nausea, dizziness, and delayed visual adaptation when moving from bright to dark environments. Serious risks include interstitial pneumonitis, which can cause potentially life-threatening breathing problems, and liver injury. Some patients develop alcohol intolerance characterized by flushing, nausea, or low blood pressure. New shortness of breath, persistent cough, jaundice, or significant vision changes require prompt medical evaluation. Patients with impaired dark adaptation should avoid driving at night.

Common Questions About Nilandron

What is Nilandron used for?

Nilandron, containing nilutamide, is used with surgical castration to treat metastatic prostate cancer. It blocks androgen receptor activity.

Is Nilandron a chemotherapy drug?

No. Nilutamide is a nonsteroidal antiandrogen used as hormonal treatment. It works by blocking the effects of male hormones on cancer cells.

Can Nilandron affect eyesight?

Yes. Nilutamide can delay the eyes' adaptation from bright to dark environments. Patients experiencing this effect should avoid nighttime driving and discuss symptoms with their clinician.

Can Nilandron cause lung problems?

Yes. Nilutamide can cause interstitial pneumonitis, a potentially serious inflammatory lung condition. New breathing difficulties or persistent coughing require immediate medical assessment.

References

DailyMed - NILANDRON (nilutamide) tablet. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5ccf0e9a-8935-4c8c-b883-b4967281eb4a. Date Accessed October 19, 2026.

Nilutamide. LiverTox. https://www.ncbi.nlm.nih.gov/books/NBK548158/. Date Accessed October 19, 2026.

Nilutamide. MedlinePlus. https://medlineplus.gov/druginfo/meds/a697044.html. Date Accessed October 19, 2026.

Nilutamide. National Cancer Institute. https://www.cancer.gov/about-cancer/treatment/drugs/nilutamide. Date Accessed October 19, 2026.

Nilutamide. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/nilutamide. Date Accessed October 19, 2026.