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Metoprolol succinate is a prescription beta-1 selective adrenergic blocker available in extended-release tablets. It is indicated for hypertension, angina pectoris, and heart failure. Current generic products include 25 mg, 50 mg, 100 mg, and 200 mg strengths, depending on the manufacturer. The extended-release formulation is designed for once-daily administration.
read more about metoprolol succinate ...Metoprolol blocks beta-1 adrenergic receptors, reducing heart rate, cardiac contractility, and sympathetic stimulation. This lowers blood pressure and decreases cardiac oxygen demand. The extended-release formulation releases metoprolol gradually to maintain beta-blocking activity across a 24-hour dosing interval.
Metoprolol succinate extended-release tablets treat hypertension in adults and children age 6 and older. They are also indicated for long-term treatment of angina and to reduce cardiovascular mortality and hospitalization in adults with heart failure. Patients with severe bradycardia, certain heart conduction disorders, cardiogenic shock, or decompensated heart failure must not receive treatment.
Adults with hypertension usually start at 25 mg to 100 mg once daily, while angina treatment commonly starts at 100 mg once daily. Heart failure treatment begins at 12.5 mg or 25 mg once daily, with gradual increases approximately every two weeks to a maximum target of 200 mg daily when tolerated. Pediatric hypertension starts at 1 mg per kg once daily, not exceeding 50 mg initially. Tablets can be divided when scored but are not crushed or chewed.
Serious concerns include slow heart rate, atrioventricular block, low blood pressure, worsening heart failure, and bronchospasm. Beta blockers can also mask early symptoms of low blood glucose. Abrupt discontinuation can worsen angina or trigger myocardial infarction, so treatment is usually reduced gradually over one to two weeks. Heart rate, blood pressure, and symptoms of worsening heart failure are monitored during dose increases.
Metoprolol succinate extended-release tablets treat hypertension, angina, and heart failure under the labeled criteria.
The extended-release tablets are taken once daily.
Adults generally start at 12.5 mg or 25 mg once daily, depending on heart failure severity.
Yes. Current extended-release tablet labeling includes hypertension treatment in children age 6 and older.
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Metoprolol Succinate. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Metoprolol-succinate. Date Accessed October 14, 2026.