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Methylphenidate hydrochloride is a prescription central nervous system stimulant and Schedule II controlled substance. Current immediate-release tablets contain 5 mg, 10 mg, or 20 mg. They are indicated for attention-deficit/hyperactivity disorder in adults and children age 6 and older and for narcolepsy. Extended-release methylphenidate products have separate dosing instructions.
read more about methylphenidate ...Methylphenidate increases dopamine and norepinephrine activity by inhibiting their reuptake into neurons. These neurotransmitters are involved in attention, alertness, and behavior. The precise mechanism responsible for its therapeutic effects in attention-deficit/hyperactivity disorder and narcolepsy is not established.
Immediate-release methylphenidate tablets treat attention-deficit/hyperactivity disorder in adults and pediatric patients age 6 and older. They are also used for narcolepsy. Patients are assessed for serious heart disease and risk of misuse before treatment. Current or recent use of a monoamine oxidase inhibitor within 14 days is a contraindication.
Children age 6 and older usually start at 5 mg twice daily before breakfast and lunch, with weekly increases of 5 mg to 10 mg when needed. Adults commonly receive 20 mg to 30 mg daily in two or three divided doses, preferably 30 to 45 minutes before meals. The maximum recommended total dose for immediate-release tablets is 60 mg daily. Extended-release products use different regimens.
Methylphenidate carries a boxed warning for abuse, misuse, and addiction, including overdose and death. Other serious concerns include sudden death in patients with serious heart disease, increased blood pressure and heart rate, psychotic or manic symptoms, slowed growth in children, peripheral vasculopathy, and priapism. Cardiovascular and behavioral symptoms are monitored during treatment.
Immediate-release methylphenidate treats attention-deficit/hyperactivity disorder from age 6 and narcolepsy.
Children age 6 and older usually start at 5 mg twice daily before breakfast and lunch.
The maximum recommended dose is 60 mg daily.
Yes. Its boxed warning concerns abuse, misuse, addiction, and the risk of overdose or death.
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