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Lisinopril is a prescription angiotensin-converting enzyme inhibitor used for hypertension in adults and children age 6 and older, adjunctive treatment of systolic heart failure, and reduction of mortality after acute myocardial infarction in hemodynamically stable adults. It is taken by mouth, commonly once daily.
read more about lisinopril ...Lisinopril inhibits angiotensin-converting enzyme, reducing production of angiotensin II and secretion of aldosterone. These changes relax blood vessels and decrease blood pressure, while also changing sodium and potassium handling in the kidneys.
Lisinopril treats hypertension in adults and qualifying children age 6 and older. It is also used with other medicines for systolic heart failure and after acute myocardial infarction in stable patients. Pregnancy, a history of ACE inhibitor-associated angioedema, and certain sacubitril-containing or aliskiren combinations are contraindications.
Adults with hypertension usually start at 10 mg once daily, with a usual dose range of 20 mg to 40 mg daily. Systolic heart failure usually starts at 5 mg once daily. Selected stable patients after an acute myocardial infarction receive 5 mg initially, 5 mg after 24 hours, 10 mg after 48 hours, and then 10 mg daily. Pediatric hypertension and kidney impairment require adjusted starting doses.
Lisinopril carries a boxed warning for fetal toxicity and is discontinued as soon as pregnancy is detected. Other serious risks include angioedema involving the face or airway, high potassium, low blood pressure, kidney dysfunction, and rare liver injury. Kidney function, potassium, and blood pressure are monitored during treatment.
Lisinopril treats hypertension, is used as an adjunct in systolic heart failure, and can reduce mortality after an acute heart attack in stable adults.
The usual starting dose is 10 mg once daily, or 5 mg in adults already taking a diuretic.
Yes. Lisinopril can cause hyperkalemia, particularly with kidney impairment or potassium-raising medicines.
Yes. The boxed warning concerns injury or death to a developing fetus.
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