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What Is Lexapro?

Lexapro is a prescription selective serotonin reuptake inhibitor containing escitalopram. It is indicated for major depressive disorder in adults and pediatric patients age 12 and older and for generalized anxiety disorder in adults and pediatric patients age 7 and older. Tablets contain 5 mg, 10 mg, or 20 mg.

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What Is Lexapro?

Lexapro is a prescription selective serotonin reuptake inhibitor containing escitalopram. It is indicated for major depressive disorder in adults and pediatric patients age 12 and older and for generalized anxiety disorder in adults and pediatric patients age 7 and older. Tablets contain 5 mg, 10 mg, or 20 mg.

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How Does Lexapro Work?

Escitalopram inhibits reuptake of serotonin by neurons in the central nervous system. This increases serotonergic activity, which is associated with its antidepressant and anti-anxiety effects.

Who Is Treated With Lexapro?

Lexapro treats major depressive disorder from age 12 and generalized anxiety disorder from age 7. Patients are screened for a personal or family history of bipolar disorder, mania, or hypomania before treatment. Monoamine oxidase inhibitors and pimozide are contraindicated with Lexapro.

How Is Lexapro Dosed?

Adults with major depressive disorder or generalized anxiety disorder start at 10 mg once daily and can increase to a maximum of 20 mg daily according to response and tolerability. Pediatric patients in the labeled age groups also start at 10 mg once daily and can increase to 20 mg after the minimum titration interval for the indication. Lexapro can be taken morning or evening with or without food.

What Serious Risks Are Linked to Lexapro?

Lexapro carries a boxed warning for increased suicidal thoughts and behaviors in pediatric and young adult patients taking antidepressants. Other serious concerns include serotonin syndrome, discontinuation reactions, seizures, activation of mania or hypomania, hyponatremia, increased bleeding, angle-closure glaucoma, and sexual dysfunction. Gradual dose reduction is recommended when treatment ends.

Frequently Asked Questions About Lexapro

What conditions does Lexapro treat?

Lexapro treats major depressive disorder and generalized anxiety disorder under age-specific criteria.

What is the usual starting dose?

The usual starting dose is 10 mg once daily.

What is the maximum recommended dose?

The maximum recommended dose is 20 mg once daily.

Does Lexapro have a boxed warning?

Yes. The boxed warning concerns increased suicidal thoughts and behaviors in pediatric and young adult patients taking antidepressants.

References

DailyMed - LEXAPRO (escitalopram) tablet, film coated and solution. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=13bb8267-1cab-43e5-acae-55a4d957630a. Date Accessed October 12, 2026.

Escitalopram. LiverTox. https://www.ncbi.nlm.nih.gov/books/NBK548395/. Date Accessed October 12, 2026.

Escitalopram. MedlinePlus. https://www.medlineplus.gov/druginfo/meds/a603005.html. Date Accessed October 12, 2026.

Escitalopram. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/146570. Date Accessed October 12, 2026.

LEXAPRO (escitalopram) Prescribing Information. AbbVie. https://www.rxabbvie.com/pdf/lexapro_pi.pdf. Date Accessed October 12, 2026.