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Latuda is a prescription atypical antipsychotic containing lurasidone hydrochloride. It is indicated for schizophrenia in adults and adolescents age 13 through 17 and for depressive episodes associated with bipolar I disorder in adults and children age 10 through 17. Adult bipolar depression treatment can be used alone or with lithium or valproate.
read more about latuda ...The exact therapeutic mechanism of lurasidone is not established. Its activity is thought to involve antagonism at dopamine D2 and serotonin 5-HT2A receptors, along with activity at other serotonin receptors.
Latuda is used for schizophrenia in adults and adolescents age 13 through 17. It is also used for bipolar depression in adults and children age 10 through 17, with adult treatment used as monotherapy or as adjunctive therapy with lithium or valproate.
Adult schizophrenia starts at 40 mg once daily with a recommended range of 40 mg to 160 mg daily. Adolescent schizophrenia uses 40 mg to 80 mg daily. Adult bipolar depression starts at 20 mg once daily with a range of 20 mg to 120 mg, while patients age 10 through 17 use 20 mg to 80 mg daily. Latuda is taken with food containing at least 350 calories.
Latuda carries boxed warnings for increased mortality in older adults with dementia-related psychosis and for suicidal thoughts and behaviors in children, adolescents, and young adults taking antidepressant therapy for bipolar depression. Other serious concerns include neuroleptic malignant syndrome, tardive dyskinesia, metabolic changes, low white blood cell counts, orthostatic hypotension, seizures, and cognitive or motor impairment. Strong CYP3A4 inhibitors and inducers are contraindicated.
Latuda treats schizophrenia and depressive episodes associated with bipolar I disorder under age-specific criteria.
The recommended starting dose is 40 mg once daily.
The recommended starting dose is 20 mg once daily in adults and patients age 10 through 17.
Yes. Latuda is taken with food containing at least 350 calories.
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LATUDA (lurasidone hydrochloride) Prescribing Information. U.S. Food and Drug Administration. https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/200603s041lbl.pdf. Date Accessed October 8, 2026.
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Lurasidone Hydrochloride. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Latuda. Date Accessed October 8, 2026.