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Ketotifen fumarate ophthalmic is an over-the-counter antihistamine eye drop. Current products contain ketotifen 0.025 percent, equivalent to ketotifen fumarate 0.035 percent. They temporarily relieve itchy eyes caused by pollen, ragweed, grass, animal hair, and dander.
read more about ketotifen ophthalmic ...Ketotifen is an H1 histamine receptor antagonist and mast cell stabilizer. It blocks histamine activity and reduces release of mediators involved in allergic eye itching.
Current over-the-counter directions apply to adults and children age 3 and older. Children younger than 3 require medical advice before use. The drops are not used for contact lens-related irritation or when the liquid has changed color or become cloudy.
Adults and children age 3 and older place one drop in the affected eye or eyes twice daily, every 8 to 12 hours, with no more than two doses per day. Contact lenses are removed before use and can be reinserted after at least 10 minutes.
Use stops and medical advice is sought for eye pain, vision changes, eye redness, or itching that worsens or lasts longer than 72 hours. The dropper tip does not touch the eye or another surface, which reduces contamination risk. Accidental swallowing requires medical help or contact with a Poison Control Center.
It temporarily relieves itchy eyes caused by common allergens such as pollen, ragweed, grass, animal hair, and dander.
One drop is placed in the affected eye or eyes twice daily, every 8 to 12 hours.
Yes. Current over-the-counter directions apply to children age 3 and older. A doctor is consulted for younger children.
Contact lenses can be reinserted at least 10 minutes after the drops are used.
Efficacy and Safety of Ketotifen Eye Drops in the Treatment of Seasonal Allergic Conjunctivitis. https://pubmed.ncbi.nlm.nih.gov/14507747/. Date Accessed October 7, 2026.
Efficacy and Tolerability of Ketotifen in the Treatment of Seasonal Allergic Conjunctivitis: Comparison Between Ketotifen 0.025% and 0.05% Eye Drops. https://pubmed.ncbi.nlm.nih.gov/30303746/. Date Accessed October 7, 2026.
Ketotifen Fumarate Ophthalmic Solution Drug Label Information. https://www.dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7e7be193-63ec-474d-a596-e22fc8b1be0f. Date Accessed October 7, 2026.
Ketotifen Ophthalmic: MedlinePlus Drug Information. https://medlineplus.gov/druginfo/meds/a604033.html. Date Accessed October 7, 2026.
Topical Ketotifen Treatment for Allergic Conjunctivitis: A Systematic Review and Meta-Analysis. https://pubmed.ncbi.nlm.nih.gov/36816214/. Date Accessed October 7, 2026.