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What Is Kenalog?

Kenalog is a triamcinolone acetonide product family. This page focuses on Kenalog-10 Injection, which contains 10 mg of triamcinolone acetonide per mL. Kenalog-10 is used only for intra-articular or intralesional administration and is distinct from Kenalog-40.

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What Is Kenalog?

Kenalog is a triamcinolone acetonide product family. This page focuses on Kenalog-10 Injection, which contains 10 mg of triamcinolone acetonide per mL. Kenalog-10 is used only for intra-articular or intralesional administration and is distinct from Kenalog-40.

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How Does Kenalog Reduce Inflammation?

Triamcinolone acetonide is a synthetic glucocorticoid corticosteroid with anti-inflammatory activity. Corticosteroid receptor activity changes expression of genes involved in inflammation and immune responses, which reduces swelling and inflammatory symptoms in treated tissues.

Who Is Treated With Kenalog-10?

Kenalog-10 is used as short-term adjunctive therapy for selected joint and soft tissue conditions including acute gouty arthritis, bursitis, tenosynovitis, epicondylitis, rheumatoid arthritis, and osteoarthritis synovitis. Intralesional use includes selected conditions such as alopecia areata, keloids, discoid lupus erythematosus, granuloma annulare, lichen planus, and psoriatic plaques.

How Is Kenalog-10 Dosed?

For intra-articular treatment, initial doses are 2.5 mg to 5 mg for smaller joints and 5 mg to 15 mg for larger joints. Intralesional doses depend on the lesion and injection site. Kenalog-10 is not given intravenously, intramuscularly, intraocularly, epidurally, or intrathecally.

What Serious Risks Are Linked to Kenalog-10?

Triamcinolone injections can cause serious hypersensitivity, immune suppression, infection, adrenal suppression, high blood pressure, glucose changes, osteoporosis, psychiatric reactions, glaucoma, and local tissue atrophy. Serious neurologic injury and death have occurred after epidural corticosteroid injection, a route not approved for Kenalog-10.

Frequently Asked Questions About Kenalog

What strength is Kenalog-10?

Kenalog-10 contains 10 mg of triamcinolone acetonide per mL.

What routes are used for Kenalog-10?

Kenalog-10 is used only by intra-articular or intralesional injection.

Is Kenalog-10 the same as Kenalog-40?

No. Kenalog-10 contains 10 mg per mL and has different labeled routes from Kenalog-40.

Can Kenalog-10 be injected epidurally?

No. Epidural administration is not approved and has been associated with serious neurologic injury.

References

KENALOG-10 (Triamcinolone Acetonide) Prescribing Information. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=653ec195-0966-478d-be47-6b1ff158e111. Date Accessed October 7, 2026.

The Efficacy of Intra-Articular Triamcinolone Acetonide 10 mg vs. 40 mg in Patients With Knee Osteoarthritis: A Non-Inferiority, Randomized, Controlled, Double-Blind, Multicenter Study. https://pubmed.ncbi.nlm.nih.gov/36737698/. Date Accessed October 7, 2026.

Treatment of Severe Alopecia Areata With Intralesional Steroid Injections. https://pubmed.ncbi.nlm.nih.gov/19852119/. Date Accessed October 7, 2026.

Triamcinolone Injection: MedlinePlus Drug Information. https://medlineplus.gov/druginfo/meds/a625028.html. Date Accessed October 7, 2026.

Intraarticular Triamcinolone Acetonide for Pain Control After Arthroscopic Knee Surgery. https://pubmed.ncbi.nlm.nih.gov/9806691/. Date Accessed October 7, 2026.