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Junel is a group of prescription combination oral contraceptives containing norethindrone acetate and ethinyl estradiol. Current products include 21-day Junel 1/20 and Junel 1.5/30 as well as Junel Fe formulations that add non-hormonal ferrous fumarate reminder tablets.
read more about junel ...Combined oral contraceptives prevent pregnancy primarily by suppressing ovulation. They also produce changes in cervical mucus and the endometrium that reduce the chance of fertilization and implantation.
Junel products are used by females of reproductive potential for pregnancy prevention. They are not used in patients at high risk for arterial or venous thrombosis, patients with current or previous breast cancer, selected liver disease, unexplained genital bleeding, or certain interacting hepatitis C regimens.
Junel 21-day products use one active tablet daily for 21 days followed by seven days without tablets. Junel Fe 28-day products use 21 active tablets followed by seven non-hormonal ferrous fumarate reminder tablets. Tablets are taken at about the same time each day.
Junel carries a boxed warning for cigarette smoking and serious cardiovascular events. Combination oral contraceptives are contraindicated in patients older than 35 who smoke. Other serious concerns include venous thromboembolism, stroke, heart attack, high blood pressure, liver disease, gallbladder disease, and abnormal uterine bleeding.
Junel contains norethindrone acetate and ethinyl estradiol.
Junel 1/20 contains 1 mg of norethindrone acetate with 20 mcg of ethinyl estradiol, while Junel 1.5/30 contains 1.5 mg with 30 mcg.
Junel Fe products include non-hormonal ferrous fumarate reminder tablets after the active hormone tablets.
Yes. The boxed warning concerns cigarette smoking and serious cardiovascular events.
A Randomized, Double-Blind Study of Six Combined Oral Contraceptives. https://pubmed.ncbi.nlm.nih.gov/6804161/. Date Accessed October 6, 2026.
Combined Hormonal Contraceptives. https://www.cdc.gov/contraception/hcp/usspr/combined-hormonal-contraceptives.html. Date Accessed October 6, 2026.
Ethinyl Estradiol and Norethindrone (Oral Contraceptives): MedlinePlus Drug Information. https://www.medlineplus.gov/druginfo/meds/a601050.html. Date Accessed October 6, 2026.
JUNEL 21 Day and JUNEL FE 28 Day Prescribing Information. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=75bb0024-8f1a-4036-9acd-006ea430f3b7. Date Accessed October 6, 2026.
U.S. Selected Practice Recommendations for Contraceptive Use, 2024. https://www.cdc.gov/mmwr/volumes/73/rr/rr7303a1.htm. Date Accessed October 6, 2026.