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Jublia is a prescription azole antifungal containing efinaconazole 10 percent topical liquid. It is indicated for onychomycosis of the toenails caused by Trichophyton rubrum or Trichophyton mentagrophytes. Current labeling establishes safety and efficacy in patients age 6 and older.
read more about jublia ...Efinaconazole inhibits fungal lanosterol 14-alpha-demethylase, an enzyme involved in synthesis of ergosterol. Ergosterol is a component of fungal cell membranes, so inhibition disrupts normal fungal membrane formation.
Jublia is used in adults and children age 6 and older with toenail onychomycosis caused by Trichophyton rubrum or Trichophyton mentagrophytes. Safety and efficacy are not established in children younger than 6.
Jublia is applied to affected toenails once daily for 48 weeks with the integrated flow-through brush applicator. The toenail, nail folds, nail bed, hyponychium, and undersurface of the nail plate are covered. Jublia is for topical use only and is not used orally, in the eyes, or intravaginally.
The most common adverse reactions reported in clinical trials were ingrown toenails, application-site dermatitis, application-site vesicles, and application-site pain. Current labeling lists no contraindications.
Jublia treats toenail onychomycosis caused by Trichophyton rubrum or Trichophyton mentagrophytes.
Jublia is applied to affected toenails once daily.
The labeled treatment course lasts 48 weeks.
Yes. Current labeling establishes safety and efficacy in patients age 6 and older.
Efinaconazole 10% Solution in the Treatment of Toenail Onychomycosis: Two Phase III Multicenter, Randomized, Double-Blind Studies. https://pubmed.ncbi.nlm.nih.gov/23177180/. Date Accessed October 6, 2026.
Efinaconazole in Onychomycosis. https://pubmed.ncbi.nlm.nih.gov/34902110/. Date Accessed October 6, 2026.
Efinaconazole Topical: MedlinePlus Drug Information. https://medlineplus.gov/druginfo/meds/a614050.html. Date Accessed October 6, 2026.
JUBLIA (Efinaconazole) Prescribing Information. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=922d4d25-c530-11e1-9b21-0800200c9a66. Date Accessed October 6, 2026.
Safety, Pharmacokinetics, and Efficacy of Efinaconazole 10% Topical Solution for Onychomycosis Treatment in Pediatric Patients. https://pubmed.ncbi.nlm.nih.gov/33026753/. Date Accessed October 6, 2026.