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Jantoven is a prescription anticoagulant containing warfarin sodium. It is used to treat or prevent venous thrombosis and pulmonary embolism, reduce thromboembolic complications associated with atrial fibrillation or cardiac valve replacement, and reduce selected thromboembolic risks after myocardial infarction.
read more about jantoven ...Warfarin inhibits regeneration of vitamin K through the VKORC1 enzyme complex. This reduces synthesis of vitamin K-dependent clotting factors II, VII, IX, and X and also affects the anticoagulant proteins C and S.
Jantoven is used when oral vitamin K antagonist anticoagulation is indicated for venous thrombosis, pulmonary embolism, atrial fibrillation, cardiac valve replacement, or selected patients after myocardial infarction. Treatment is individualized according to the indication, bleeding risk, interacting medicines, diet, and INR response.
When CYP2C9 and VKORC1 genotypes are not known, the usual initial dose is 2 mg to 5 mg once daily. Typical maintenance doses range from 2 mg to 10 mg once daily, but the actual dose is adjusted according to INR results. INR is checked frequently when treatment begins and periodically after stabilization.
Jantoven carries a boxed warning for major or fatal bleeding. Other serious concerns include skin or tissue necrosis, calciphylaxis, acute kidney injury during excessive anticoagulation, systemic atheroemboli, and limb ischemia in patients with heparin-induced thrombocytopenia. Pregnancy is contraindicated except in selected women with mechanical heart valves.
Jantoven is a vitamin K antagonist anticoagulant containing warfarin sodium.
The usual initial dose is 2 mg to 5 mg once daily, followed by adjustment according to INR response.
Warfarin has a narrow therapeutic range, and medicines, diet, illness, and other factors can change the anticoagulant response.
Yes. The boxed warning concerns major or fatal bleeding.
JANTOVEN (Warfarin Sodium) Prescribing Information. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=19a69a72-ac5d-45d5-a94d-a5aaecbe4730. Date Accessed October 5, 2026.
Stroke Prevention in Atrial Fibrillation Study. Final Results. https://pubmed.ncbi.nlm.nih.gov/1860198/. Date Accessed October 5, 2026.
Warfarin: MedlinePlus Drug Information. https://medlineplus.gov/druginfo/meds/a682277.html. Date Accessed October 5, 2026.
Warfarin. https://www.ncbi.nlm.nih.gov/books/NBK470313/. Date Accessed October 5, 2026.
Warfarin in the Prevention of Stroke Associated With Nonrheumatic Atrial Fibrillation. https://pubmed.ncbi.nlm.nih.gov/1406859/. Date Accessed October 5, 2026.