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Insulin detemir is a long-acting human insulin analog formerly marketed in the United States as Levemir. FDA lists the Levemir vial and prefilled pen presentations as discontinued. Its final U.S. labeling covered adults and children with diabetes mellitus.
read more about insulin detemir ...Insulin detemir lowers blood glucose by increasing glucose uptake in skeletal muscle and fat and decreasing glucose production in the liver. It also reduces lipolysis and proteolysis and increases protein synthesis. Its prolonged action supported basal insulin treatment.
Levemir was indicated to improve glycemic control in adults and pediatric patients with diabetes mellitus. In type 1 diabetes, it was used with rapid-acting or short-acting insulin. It was not recommended for treatment of diabetic ketoacidosis.
Levemir was injected subcutaneously once daily or in divided doses twice daily. Once-daily treatment was given with the evening meal or at bedtime. For insulin-naive type 2 diabetes, the labeled starting dose was 10 units or 0.1 to 0.2 units per kg once daily in the evening or divided into two daily doses.
Major risks included hypoglycemia, hypokalemia, severe hypersensitivity, medication errors, lipodystrophy, localized cutaneous amyloidosis, and fluid retention or heart failure with thiazolidinediones. Levemir was administered only by subcutaneous injection and was not used intravenously or in an insulin pump.
Insulin detemir was a long-acting human insulin analog used as basal insulin.
No. FDA lists the Levemir vial and prefilled pen presentations as discontinued.
The labeled starting dose was 10 units or 0.1 to 0.2 units per kg once daily in the evening or divided into two daily doses.
No. Levemir labeling directed against use in insulin pumps.
Diabetes Treatments. https://www.novonordisk-us.com/products/diabetes.html. Date Accessed October 5, 2026.
Insulin Detemir (rDNA Origin) Injection: MedlinePlus Drug Information. https://medlineplus.gov/druginfo/meds/a606012.html. Date Accessed October 5, 2026.
Insulin Detemir: A Review of Its Use in the Management of Diabetes Mellitus. https://pubmed.ncbi.nlm.nih.gov/23110609/. Date Accessed October 5, 2026.
LEVEMIR (Insulin Detemir) Prescribing Information. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=d38d65c1-25bf-401d-9c7e-a2c3222da8af. Date Accessed October 5, 2026.
Purple Book Product Details for Levemir. https://purplebooksearch.fda.gov/index.cfm?blaNo=021536&event=productdetails. Date Accessed October 5, 2026.