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Granisetron is an anti-nausea medicine in the serotonin 5-HT3 receptor antagonist class. It is used to prevent nausea and vomiting associated with cancer chemotherapy or radiation therapy. It comes in formulations that include tablets, injections, and a skin patch.
read more about granisetron ...Granisetron blocks certain serotonin receptors involved in triggering nausea and vomiting. It is usually given before treatment that could cause these symptoms. The timing and duration depend on the formulation.
Tablets are taken according to the schedule prescribed around chemotherapy or radiation therapy. Injections are given by a healthcare professional. A granisetron patch is applied before chemotherapy and worn for the prescribed period.
Headache and constipation can occur with granisetron. Seek prompt care for fainting, an irregular heartbeat, or signs of an allergic reaction. Agitation, fever, muscle stiffness, and confusion can be signs of serotonin syndrome, particularly when interacting medicines are involved.
Tell your care team about all medicines you take, including medicines that affect serotonin or heart rhythm. Mention any history of heart rhythm problems before treatment. Follow the instructions for your specific formulation rather than using directions from a different granisetron product.
Its main labeled use is preventing nausea and vomiting around specified treatments. Follow your prescribed plan and tell your care team if symptoms break through.
Yes. The patch is used to prevent nausea and vomiting from chemotherapy and has its own application schedule.
Yes. Constipation is a reported side effect of oral granisetron.
QT prolongation has been reported with granisetron. Tell your clinician about heart rhythm conditions and medicines that may also affect the QT interval.
Granisetron. MedlinePlus. https://medlineplus.gov/druginfo/meds/a601211.html. Date Accessed October 6, 2026.
Granisetron (intravenous route) - Side effects & uses. Mayo Clinic. https://www.mayoclinic.org/drugs-supplements/granisetron-intravenous-route/description/drg-20067622. Date Accessed October 6, 2026.
Granisetron Injection. MedlinePlus. https://medlineplus.gov/druginfo/meds/a694011.html. Date Accessed October 6, 2026.
Granisetron tablets. Cleveland Clinic. https://my.clevelandclinic.org/health/drugs/19104-granisetron-tablets. Date Accessed October 6, 2026.
Granisetron Transdermal Patch. MedlinePlus. https://www.medlineplus.gov/druginfo/meds/a609015.html. Date Accessed October 6, 2026.