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What Is Gocovri?

Gocovri is an extended-release form of amantadine used in Parkinson's disease. It treats involuntary movements associated with levodopa therapy. It is also used alongside levodopa and carbidopa for periods when Parkinson's symptoms return between doses.

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What Is Gocovri?

Gocovri is an extended-release form of amantadine used in Parkinson's disease. It treats involuntary movements associated with levodopa therapy. It is also used alongside levodopa and carbidopa for periods when Parkinson's symptoms return between doses.

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When Gocovri Is Used

Involuntary movements caused by levodopa are called dyskinesia. Periods when levodopa's benefit wears off are called off episodes. Gocovri has labeled uses for both problems in the specified treatment settings.

How to Take Gocovri

Gocovri is taken once daily at bedtime. Capsules should be swallowed whole, although their contents may be sprinkled on a small amount of soft food as directed in the label. The dose may need adjustment for reduced kidney function.

Possible Side Effects

Hallucinations, dizziness, dry mouth, constipation, and swelling of the legs or feet can occur. Gocovri may also cause sleepiness or a sudden episode of falling asleep during daily activities. Report new hallucinations, mood changes, or vision changes to a clinician promptly.

Stopping and Changing Treatment

Do not stop Gocovri suddenly without medical guidance. Abrupt withdrawal can worsen Parkinson's symptoms and cause confusion or other serious effects. Gocovri cannot be substituted dose for dose with other amantadine products.

Frequently Asked Questions About Gocovri

What is the active ingredient in Gocovri?

Its active ingredient is amantadine. Gocovri is an extended-release formulation with its own dosing instructions.

When is Gocovri taken?

It is taken once daily at bedtime. Follow the prescribed dose, which may differ if kidney function is reduced.

Can Gocovri cause hallucinations?

Yes. Contact your clinician if you see or hear things that are not present.

Can Gocovri be stopped abruptly?

Sudden discontinuation can cause serious symptoms. Ask the prescriber for a plan before stopping it.

References

Amantadine. MedlinePlus. https://medlineplus.gov/druginfo/meds/a682064.html. Date Accessed October 6, 2026.

Amantadine (oral route) - Side effects & dosage. Mayo Clinic. https://www.mayoclinic.org/drugs-supplements/amantadine-oral-route/description/drg-20061695. Date Accessed October 6, 2026.

Amantadine Extended-Release Oral Capsules. Cleveland Clinic. https://my.clevelandclinic.org/health/drugs/24365-amantadine-extended-release-oral-capsules. Date Accessed October 6, 2026.

Effects of Gocovri (Amantadine) Extended Release Capsules on Non-Motor Symptoms in Patients with Parkinson's Disease and Dyskinesia. PubMed Central. https://pmc.ncbi.nlm.nih.gov/articles/PMC8140024/. Date Accessed October 6, 2026.

GOCOVRI- amantadine capsule, coated pellets. DailyMed (National Library of Medicine). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2bee0631-0028-1314-e063-6394a90aaaed. Date Accessed October 6, 2026.