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Firazyr is the brand name for icatibant, a medicine injected under the skin. It treats sudden attacks of hereditary angioedema in adults ages 18 and older. These attacks can cause swelling in areas such as the skin, abdomen, or throat.
read more about firazyr ...Firazyr treats an acute hereditary angioedema attack after symptoms begin. It is not a daily medicine for preventing attacks. Swelling involving the throat needs immediate medical attention even after Firazyr is given.
Hereditary angioedema attacks involve the effects of a substance called bradykinin. Firazyr blocks bradykinin B2 receptors. This helps reduce the swelling associated with an attack.
Firazyr comes in a prefilled syringe for injection under the skin. A patient can give the injection after receiving training from a healthcare professional. Further doses can be used when symptoms persist or return, following the prescribed timing and daily limit.
Redness, pain, or swelling at the injection site is common. Dizziness, rash, or fever can also occur. A throat attack can obstruct breathing, so seek immediate care in a medical facility after treating one.
No. It treats an attack that is already happening. Ask a specialist about preventive treatment if attacks recur.
Yes, after training and when your care plan directs you to do so. A healthcare professional should explain when to seek further treatment.
Use Firazyr as directed and seek immediate medical attention. Breathing can become obstructed even after an injection.
Its U.S. labeling is for adults ages 18 and older. A specialist can advise on treatment options for a child with hereditary angioedema.
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Icatibant (subcutaneous route) - Side effects & dosage. Mayo Clinic. https://www.mayoclinic.org/drugs-supplements/icatibant-subcutaneous-route/description/drg-20075176. Date Accessed October 6, 2026.
Icatibant injection. MedlinePlus. https://www.medlineplus.gov/druginfo/meds/a623036.html. Date Accessed October 6, 2026.
Icatibant solution for injection. Cleveland Clinic. https://my.clevelandclinic.org/health/drugs/18857-icatibant-solution-for-injection. Date Accessed October 6, 2026.
Randomized placebo-controlled trial of the bradykinin B2 receptor antagonist icatibant for the treatment of acute attacks of hereditary angioedema: the FAST-3 trial. PubMed. https://pubmed.ncbi.nlm.nih.gov/22123383/. Date Accessed October 6, 2026.