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Fenofibrate is a prescription medicine used to improve certain blood fat levels. It belongs to a group of medicines called fibrates. It is used alongside dietary changes, especially when triglycerides are severely elevated.
read more about fenofibrate ...Fenofibrate can lower severely elevated triglycerides in adults. Certain products are also approved to lower elevated LDL cholesterol when recommended LDL-lowering therapy cannot be used. A clinician selects treatment based on lipid test results and other health factors.
Fenofibrate activates a receptor involved in processing fats in the body. This increases the breakdown of triglyceride-rich particles in the blood. It can also change other cholesterol measurements.
Fenofibrate is taken by mouth, usually once daily. Products differ in strength and directions, so follow the instructions for the exact prescription. A clinician checks lipid levels and kidney function during treatment.
Fenofibrate can affect liver tests and, rarely, cause serious liver injury. Muscle injury is another concern, particularly when it is taken with a statin or in people with kidney problems. Report unexplained muscle pain or weakness to a clinician promptly.
No. It is a fibrate and works differently from statins. A clinician sometimes prescribes both after considering the added muscle risk.
Yes. It is used with dietary changes to lower severely elevated triglycerides in adults.
They may need a lower starting dose or a different treatment. Severe kidney impairment can rule out fenofibrate use.
No. Strengths and instructions vary between products. Follow the label for the exact formulation prescribed.
Fenofibrate. MedlinePlus. https://medlineplus.gov/druginfo/meds/a601052.html. Date Accessed October 6, 2026.
Fenofibrate (oral route) - Side effects & dosage. Mayo Clinic. https://www.mayoclinic.org/drugs-supplements/fenofibrate-oral-route/description/drg-20068427. Date Accessed October 6, 2026.
FENOFIBRATE tablet. DailyMed (National Library of Medicine). https://www.dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=44efa0d1-19d6-9696-e063-6394a90a068d. Date Accessed October 6, 2026.
Fenofibrate Tablets. Cleveland Clinic. https://my.clevelandclinic.org/health/drugs/20555-fenofibrate-tablets. Date Accessed October 6, 2026.
Fibrates. MedlinePlus. https://www.medlineplus.gov/ency/patientinstructions/000789.htm. Date Accessed October 6, 2026.