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Encapsulating peritoneal sclerosis is a rare but serious condition where thick fibrous tissue forms around the intestines. This tissue can restrict bowel movement and cause obstruction. It is most often associated with long-term peritoneal dialysis. The condition can progress gradually or present suddenly.
read more about encapsulating peritoneal sclerosis ...The condition is most commonly linked to prolonged peritoneal dialysis. Chronic inflammation of the peritoneum plays a major role. Repeated infections and exposure to dialysis solutions can contribute. In rare cases, it may occur without a clear cause.
Symptoms include abdominal pain, nausea, vomiting, and weight loss. Bowel obstruction may develop as the condition advances. Some individuals experience reduced appetite and bloating. Symptoms often worsen over time.
Diagnosis usually involves imaging studies such as CT scans. Imaging may show thickened peritoneal membranes and trapped bowel loops. Clinical history is important, especially dialysis duration. Diagnosis can be challenging in early stages.
Encapsulating peritoneal sclerosis can become serious, so early recognition and specialist care matter. Treatment often includes managing nutrition, addressing obstruction symptoms, and reviewing dialysis options if relevant. Some cases require surgery to remove scar tissue and free the intestines. With timely care and follow-up, many people can reduce complications and improve day-to-day comfort.
People on long-term peritoneal dialysis face the highest risk.
Early cases may stabilize, but advanced disease is often progressive.
No, surgery is reserved for severe or obstructive cases.
It can be serious if bowel obstruction or malnutrition develops.
National Institutes of Health (NIH). "Encapsulating Peritoneal Sclerosis." https://pubmed.ncbi.nlm.nih.gov/24824503/
National Center for Biotechnology Information (NCBI). "Encapsulating Peritoneal Sclerosis: A rare but devastating complication of long-term peritoneal dialysis." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105702/
American Society of Nephrology. "Encapsulating Peritoneal Sclerosis in Long-Term PD Patients." https://jasn.asnjournals.org/content/16/9/2761
Kidney International. "Diagnosis and Management of EPS." https://www.kidney-international.org/article/S0085-2538(15)60060-1/fulltext
Cleveland Clinic. "Peritoneal Dialysis and Its Complications." https://my.clevelandclinic.org/health/treatments/12196-peritoneal-dialysis