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Enalapril maleate is a prescription angiotensin-converting enzyme inhibitor. It treats hypertension, symptomatic heart failure, and clinically stable asymptomatic left ventricular dysfunction with an ejection fraction of 35 percent or less. Oral tablets come in 2.5 mg, 5 mg, 10 mg, and 20 mg strengths.
read more about enalapril ...After absorption, enalapril is converted to enalaprilat, its active form. Enalaprilat inhibits angiotensin-converting enzyme, reducing formation of angiotensin II and decreasing aldosterone secretion. These effects reduce vasoconstriction and lower activity of the renin-angiotensin-aldosterone system.
Enalapril treats hypertension in adults and pediatric patients older than 1 month. It also treats symptomatic heart failure and reduces progression to overt heart failure in clinically stable patients with asymptomatic left ventricular dysfunction and an ejection fraction of 35 percent or less.
Adults with hypertension who are not taking a diuretic commonly start at 5 mg once daily, with a usual range of 10 mg to 40 mg daily. Symptomatic heart failure starts at 2.5 mg and is titrated toward 2.5 mg to 20 mg twice daily. Kidney impairment can require a lower starting dose.
Enalapril carries a boxed warning for fetal toxicity and is stopped when pregnancy is detected. Other serious concerns include angioedema, severe low blood pressure, kidney impairment, high potassium, and rare liver failure or blood-cell abnormalities. Kidney function and serum potassium are monitored during treatment.
Yes. Enalapril is converted to enalaprilat, which inhibits angiotensin-converting enzyme.
Adults not taking a diuretic commonly start with 5 mg once daily.
Yes. Current labeling includes pediatric hypertension treatment in patients older than 1 month.
Yes. The boxed warning concerns fetal toxicity from medicines that act directly on the renin-angiotensin system.
Enalapril. https://medlineplus.gov/druginfo/meds/a686022.html. Date Accessed September 29, 2026.
Enalapril. https://www.ncbi.nlm.nih.gov/books/NBK557708/. Date Accessed September 29, 2026.
Enalapril Maleate Oral Solution Prescribing Information. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c7934b45-eb6b-44c1-bd2c-ef0fa10850c1. Date Accessed September 29, 2026.
Enalapril Maleate Tablets Prescribing Information. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=7077d32e-4b06-4d48-ba0c-6db2f8ebe08c. Date Accessed September 29, 2026.
VASOTEC (Enalapril Maleate) Prescribing Information. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=39631f1f-5d19-43c1-b504-bf56d991ed97. Date Accessed September 29, 2026.