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What Is Dextroamphetamine?

Dextroamphetamine sulfate is a prescription central nervous system stimulant and Schedule II controlled substance. Current tablet labeling includes narcolepsy and attention deficit disorder with hyperactivity as part of a broader treatment program in pediatric patients. Tablets commonly come in 5 mg and 10 mg strengths.

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What Is Dextroamphetamine?

Dextroamphetamine sulfate is a prescription central nervous system stimulant and Schedule II controlled substance. Current tablet labeling includes narcolepsy and attention deficit disorder with hyperactivity as part of a broader treatment program in pediatric patients. Tablets commonly come in 5 mg and 10 mg strengths.

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How Does Dextroamphetamine Affect the Central Nervous System?

Dextroamphetamine is a sympathomimetic amine with central nervous system stimulant activity. The exact mechanism responsible for its mental and behavioral effects in attention disorders is not established. Peripheral actions include increases in systolic and diastolic blood pressure and weak bronchodilator and respiratory stimulant activity.

Who Is Treated With Dextroamphetamine?

Dextroamphetamine tablets are indicated for narcolepsy and for attention deficit disorder with hyperactivity in pediatric patients as part of a total treatment program. Current professional labeling describes ADHD use from ages 3 to 16 and states that treatment is not recommended for children younger than 3.

How Are Dextroamphetamine Tablets Dosed?

For ADHD, children age 3 to 5 start at 2.5 mg daily. Patients age 6 and older start at 5 mg once or twice daily, with weekly 5 mg increases when needed. Doses above 40 mg daily are rarely needed. Narcolepsy dosing usually ranges from 5 mg to 60 mg daily in divided doses.

What Serious Risks Are Linked to Dextroamphetamine?

Dextroamphetamine carries a boxed warning for abuse, misuse, addiction, overdose, and death. Other serious concerns include increased blood pressure and heart rate, psychiatric reactions, serotonin syndrome, seizures, growth suppression, tics, glaucoma, and cardiac risk in susceptible patients. Monoamine oxidase inhibitor use within 14 days is contraindicated.

Frequently Asked Questions About Dextroamphetamine

Is dextroamphetamine a stimulant?

Yes. Dextroamphetamine is a central nervous system stimulant and a Schedule II controlled substance.

What conditions does dextroamphetamine treat?

Current tablet labeling includes narcolepsy and pediatric attention deficit disorder with hyperactivity.

What is a common starting dose for children age 6 and older with ADHD?

The labeled starting dose is 5 mg once or twice daily.

Does dextroamphetamine have a boxed warning?

Yes. The boxed warning covers abuse, misuse, addiction, overdose, and death.

References

DailyMed - DEXTROAMPHETAMINE SULFATE tablet. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=24163442-dd03-4066-a6ed-eb7e292b700b. Date Accessed September 24, 2026.

DailyMed - DEXTROAMPHETAMINE SULFATE tablet. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=9acdf000-fefe-47c7-a44c-0f7a65c5c05c. Date Accessed September 24, 2026.

Dextroamphetamine. MedlinePlus. https://medlineplus.gov/druginfo/meds/a605027.html. Date Accessed September 24, 2026.

Dextroamphetamine. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/51-64-9. Date Accessed September 24, 2026.

Dextroamphetamine-Amphetamine. StatPearls. https://www.ncbi.nlm.nih.gov/books/NBK507808/. Date Accessed September 24, 2026.