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Crestor is a prescription statin containing rosuvastatin. It is used to reduce major cardiovascular events in adults at increased cardiovascular risk and to lower LDL cholesterol in several lipid disorders. Current indications also include heterozygous familial hypercholesterolemia from age 8 and homozygous familial hypercholesterolemia from age 7.
read more about crestor ...Rosuvastatin inhibits HMG-CoA reductase, the rate-limiting enzyme involved in cholesterol synthesis. Reduced cholesterol production increases hepatic uptake of LDL particles from the blood. This lowers LDL cholesterol and can also reduce triglycerides while raising HDL cholesterol to varying degrees.
Crestor is used in adults at increased risk for major cardiovascular events and in adults with hypercholesterolemia, primary dysbetalipoproteinemia, or hypertriglyceridemia. It also slows progression of atherosclerosis in adults and treats heterozygous familial hypercholesterolemia from age 8 and homozygous familial hypercholesterolemia from age 7.
Adults take 5 mg to 40 mg once daily with or without food. LDL cholesterol can be reassessed as early as four weeks after treatment starts. Asian patients start at 5 mg once daily. Severe kidney impairment without hemodialysis also starts at 5 mg once daily and has a 10 mg daily maximum.
Serious risks include myopathy, rhabdomyolysis, immune-mediated necrotizing myopathy, and liver injury. Protein in the urine and blood in the urine occur more often at 40 mg and are generally transient. Crestor can also increase blood glucose and HbA1c. Drug interactions can require lower dose limits or avoidance.
Crestor contains rosuvastatin, an HMG-CoA reductase inhibitor commonly called a statin.
Crestor is taken once daily, with or without food, at any time of day.
The recommended adult dosage range is 5 mg to 40 mg once daily.
Yes. Rosuvastatin can cause myopathy and rhabdomyolysis, with risk influenced by dose, medical conditions, and interacting medicines.
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DailyMed - ROSUVASTATIN CALCIUM tablet, film coated. https://www.dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5c992d3d-d754-48b6-a267-1451208352ed. Date Accessed September 24, 2026.
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