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What Is Coreg?

Coreg is a prescription medicine containing carvedilol, an alpha and beta adrenergic blocker. It is approved for mild to severe chronic heart failure, left ventricular dysfunction after myocardial infarction in clinically stable patients, and hypertension. Tablets are taken with food to slow absorption and reduce orthostatic effects.

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What Is Coreg?

Coreg is a prescription medicine containing carvedilol, an alpha and beta adrenergic blocker. It is approved for mild to severe chronic heart failure, left ventricular dysfunction after myocardial infarction in clinically stable patients, and hypertension. Tablets are taken with food to slow absorption and reduce orthostatic effects.

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How Does Coreg Affect the Heart and Blood Vessels?

Carvedilol blocks beta adrenergic receptors and alpha1 adrenergic receptors. Beta blockade reduces heart rate and cardiac workload, while alpha1 blockade causes vasodilation and lowers peripheral vascular resistance. These combined actions reduce blood pressure and cardiac stress.

Who Is Treated With Coreg?

Coreg is used for mild to severe chronic heart failure of ischemic or cardiomyopathic origin. It also reduces cardiovascular mortality in clinically stable patients after myocardial infarction when left ventricular ejection fraction is 40 percent or less. Coreg is also used for hypertension alone or with other antihypertensive medicines.

How Are Coreg Tablets Dosed?

Heart failure treatment starts at 3.125 mg twice daily and increases at intervals of at least two weeks as tolerated. Post-infarction left ventricular dysfunction commonly starts at 6.25 mg twice daily and targets 25 mg twice daily. Hypertension starts at 6.25 mg twice daily and can increase to 25 mg twice daily.

What Serious Risks Are Linked to Coreg?

Coreg can cause slow heart rate, low blood pressure, dizziness, fainting, worsening heart failure, fluid retention, bronchospasm, and changes in blood glucose. Abrupt discontinuation can worsen coronary artery disease and trigger serious cardiac events. Severe bradycardia, advanced heart block, cardiogenic shock, decompensated heart failure, bronchial asthma, and severe liver impairment are contraindications.

Frequently Asked Questions About Coreg

What medicine is in Coreg?

Coreg contains carvedilol, an alpha and beta adrenergic blocker.

What conditions does Coreg treat?

Coreg treats chronic heart failure, selected left ventricular dysfunction after myocardial infarction, and hypertension.

Should Coreg be taken with food?

Yes. Coreg is taken with food to slow absorption and reduce orthostatic effects.

Can Coreg be stopped suddenly?

No. Abrupt discontinuation can worsen coronary artery disease and trigger serious cardiac events.

References

Carvedilol. MedlinePlus. https://medlineplus.gov/druginfo/meds/a697042.html. Date Accessed September 23, 2026.

Carvedilol. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/2585. Date Accessed September 23, 2026.

Carvedilol. StatPearls. https://www.ncbi.nlm.nih.gov/books/NBK534868/. Date Accessed September 23, 2026.

DailyMed - CARVEDILOL tablet, film coated. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=52785a22-ddca-4f5b-8579-5974df2a9a4e. Date Accessed September 23, 2026.

DailyMed - COREG (carvedilol) tablet, film coated. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=07c619c6-4a0c-445e-94fa-664a54f68a39. Date Accessed September 23, 2026.