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Ceftriaxone is a prescription broad-spectrum cephalosporin antibacterial given by intravenous or intramuscular injection. It is used for selected bacterial infections involving the respiratory tract, ears, skin, urinary tract, blood, bones, joints, abdomen, and central nervous system. It also has labeled uses for selected gonococcal infections and surgical infection prevention.
read more about ceftriaxone ...Ceftriaxone is bactericidal and inhibits bacterial cell wall synthesis. It binds penicillin-binding proteins and disrupts formation of peptidoglycan needed for bacterial cell wall strength. Ceftriaxone retains activity against some bacteria that produce beta-lactamases, though resistance can arise through beta-lactamase activity, altered binding proteins, or reduced permeability.
Ceftriaxone is labeled for selected lower respiratory tract infections, acute bacterial otitis media, skin infections, complicated or uncomplicated urinary tract infections, gonorrhea, pelvic inflammatory disease, septicemia, bone and joint infections, intra-abdominal infections, and bacterial meningitis. It is also used before selected surgical procedures to reduce postoperative infection risk.
Adults commonly receive 1 g to 2 g daily by intravenous or intramuscular administration, given once daily or in two divided doses according to infection severity. The total adult daily dose should not exceed 4 g. Pediatric dosing is weight based and differs for skin infections, otitis media, serious infections, and meningitis.
Serious risks include anaphylaxis, Clostridioides difficile-associated diarrhea, neurologic reactions such as encephalopathy or seizures, severe skin reactions, and ceftriaxone-calcium precipitation. Premature or hyperbilirubinemic neonates should not receive ceftriaxone. It is contraindicated in neonates age 28 days or younger who require intravenous calcium-containing fluids.
Ceftriaxone is given by intravenous or intramuscular injection.
The usual adult daily dose is 1 g to 2 g, with a maximum of 4 g daily.
Ceftriaxone can displace bilirubin and can form dangerous precipitates with intravenous calcium in susceptible neonates.
Yes. Ceftriaxone is labeled for meningitis caused by selected susceptible bacteria.
Ceftriaxone Injection. MedlinePlus. https://medlineplus.gov/druginfo/meds/a685032.html. Date Accessed September 21, 2026.
Ceftriaxone. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Ceftriaxone. Date Accessed September 21, 2026.
Cephalosporins. StatPearls. https://www.ncbi.nlm.nih.gov/books/NBK551517/. Date Accessed September 21, 2026.
DailyMed - CEFTRIAXONE injection, powder, for solution. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=86ec0a92-a552-4a6d-9125-a54f95e43392. Date Accessed September 21, 2026.
DailyMed - CEFTRIAXONE injection, powder, for solution. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=96f3fc1e-84f4-4e9b-91ac-19a1692f227a. Date Accessed September 21, 2026.