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Carvedilol is a prescription alpha and beta adrenergic blocker. It is approved for mild to severe chronic heart failure, left ventricular dysfunction after myocardial infarction in clinically stable patients, and hypertension. Immediate-release tablets come in 3.125 mg, 6.25 mg, 12.5 mg, and 25 mg strengths and are taken with food.
read more about carvedilol ...Carvedilol blocks beta receptors and alpha1 adrenergic receptors. Beta blockade reduces heart rate and cardiac output, while alpha1 blockade causes vasodilation and lowers peripheral vascular resistance. These actions reduce blood pressure and cardiac workload. The exact basis for its survival benefit in chronic heart failure is not fully established.
Carvedilol treats mild to severe chronic heart failure of ischemic or cardiomyopathic origin. It also reduces cardiovascular mortality in clinically stable patients with left ventricular ejection fraction of 40 percent or less after myocardial infarction. Carvedilol is also approved for hypertension, alone or with other antihypertensive medicines.
Heart failure treatment starts at 3.125 mg twice daily and increases at intervals of at least two weeks toward 25 mg twice daily as tolerated. Hypertension starts at 6.25 mg twice daily and can increase to 25 mg twice daily. Post-infarction left ventricular dysfunction commonly starts at 6.25 mg twice daily. Tablets are taken with food.
Carvedilol can cause slow heart rate, low blood pressure, worsening heart failure, fluid retention, and dizziness. Abrupt discontinuation can worsen coronary artery disease and trigger serious cardiac events. Contraindications include bronchial asthma, advanced heart block, severe bradycardia without a pacemaker, cardiogenic shock, decompensated heart failure requiring intravenous inotropes, and severe liver impairment.
Yes. Carvedilol blocks beta receptors and also has alpha1 adrenergic blocking activity.
Carvedilol treats chronic heart failure, selected left ventricular dysfunction after myocardial infarction, and hypertension.
Yes. Immediate-release carvedilol tablets are taken with food to reduce orthostatic effects.
No. Abrupt discontinuation can worsen coronary artery disease and trigger serious cardiac events.
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DailyMed - CARVEDILOL tablet, film coated. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=52785a22-ddca-4f5b-8579-5974df2a9a4e. Date Accessed September 21, 2026.
DailyMed - COREG (carvedilol) tablet, film coated. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=07c619c6-4a0c-445e-94fa-664a54f68a39. Date Accessed September 21, 2026.